Novel oral sustained release technology: A concise review.

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dc.contributor.authorParashar, Tarun
dc.contributor.authorSoniya
dc.contributor.authorSingh, Vishal
dc.contributor.authorSingh, Gaurav
dc.contributor.authorTyagi, Satyanand
dc.contributor.authorPatel, Chirag
dc.contributor.authorGupta, Anil
dc.date.accessioned2013-04-29T08:14:52Z
dc.date.available2013-04-29T08:14:52Z
dc.date.issued2013-02
dc.description.abstractThe advantage of administering a single dose of a drug that is released over an extended period of time instead of numerous doses is now a day’s area of interest for formulation scientists in Pharmaceutical industry. There are several advantages of sustained release drug delivery over conventional dosage forms like improved patient compliance due to less frequent drug administration, maximum utilization of the drug, increased safety margin of potent drug, reduction of fluctuation in steady-state drug levels, reduction in healthcare costs through improved therapy and shorter treatment period. Wide varieties of polymers like Hydroxy Propyl Methyl Cellulose (HPMC), Carboxy Methyl Cellulose (CMC), Ethyl Cellulose (EC), Cellulose Acetate Phthalate, HPMC K100M, Xanthan gum, Carrageenan gum, Karaya gum, HPMC K15, Carbopol 971P and Carbopol 974P etc. are available for retarding the release rate of drugs hence sustains the action of drugs. This review article describes the basic information regarding sustained-release formulation, its advantages, disadvantages, selection of drug for sustain release, mechanism of release, different types, and factor involved in oral sustained-release dosage form design.en_US
dc.identifier.citationParashar Tarun, Soniya, Singh Vishal, Singh Gaurav, Tyagi Satyanand, Patel Chirag, Gupta Anil. Novel oral sustained release technology: A concise review. International Journal of Research and Development in Pharmacy and Life Sciences. 2013 Feb-Mar; 2(2): 262-269.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/146395
dc.language.isoenen_US
dc.source.urihttps://www.ijrdpl.com/docs/currentissuevolume02issue02februarymarch2013pl/1.pdfen_US
dc.subjectSustained-releaseen_US
dc.subjectConventional dosage formen_US
dc.subjectdissolutionen_US
dc.subjectDiffusionen_US
dc.subjectOral controlled release systemen_US
dc.titleNovel oral sustained release technology: A concise review.en_US
dc.typeArticleen_US
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