Image analysis in In Vivo Stem Cell Tracking.
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Date
2011-10
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Abstract
Regenerative medicine has begun to define a new perspective of future clinical practice.
The lack of basic data regarding to basic stem cell biology-survival, migration,
differentiation, integration in a real time manner when transplanted into damaged tissue
remains a major challenge for design stem cell therapies. So, visualization of injected
stem cells provides additional insight into the future therapeutic benefits. Although current
imaging modalities including magnetic resonance imaging, positron emission
tomography, single photon emission computed tomography, bioluminescence imaging,
and fluorescence imaging offer some morphological as well as functional information,
they lack the ability to assess and track in vivo biological phenomenon, a pivotal link for
greater mechanistic understanding following cell-based intervention. This review will
therefore discuss currently available in vivo imaging modalities and image processing
techniques which may potentiate this field of research.
Description
Keywords
Stem cell, tracking, In-vivo, image analysis
Citation
Rabbani Hossein, Javanmard Shaghayegh Haghjooy. Image analysis in In Vivo Stem Cell Tracking. Annual Review & Research in Biology. 2011 Oct-Dec; 1(4): 123-142.