Hormonal Receptors Status of Breast Cancer in Northeastern Thai Women : An Analysis of 241 cases at Srinagarind Hospital

Simple item page
dc.contributor.authorSupinda Koonmeeen_US
dc.contributor.authorSarithorn Sirithunyapornen_US
dc.contributor.authorEm-orn Phanomsrien_US
dc.date.accessioned2011-02-24T04:34:04Z
dc.date.available2011-02-24T04:34:04Z
dc.date.created2010-02-22en_US
dc.date.issued2010-02-22en_US
dc.description.abstractBackground: The most effective treatment for  breast cancer cases  is based on an abnormal oncogene of the cancer cell and the finding of protein expression. The prognostic factor depends on  hormonal receptors status and  biological characteristics such as histological grading, tumor size or  nodal metastasis.Objective:   To study prognostic factors including estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) status in Northeastern Thai female breast cancer.     Materials and Methods:          A retrospective review was performed on 294 patients who have been diagnosed  with  breast cancer by hormonal study at department of Pathology, Khon Kaen University (Srinagarind hospital) during January 2004 – June 2006.Result:         The mean and median ages were 52.21 year and 53 year, respectively. The 89.83 % of the patients were  invasive ductal carcinoma and 50.93 % in histological grading II. The ER+, PR+ and HER2  positive were 53.1 %,  42.26 % and  27.15  %, respectively. The proportion of ER+PR+, ER+PR-,  ER-PR+, ER-PR-  and HER2 were  4.7, 20.5, 29.4 and  44.2 % , respectively.Conclusion: The present study showed  that  the highest chance to get HER2 positive was when both ER and PR were negative.Key words: Breast Cancer, Estrogen Receptor, Progesterone Receptor, Human Epidermal Growth Factor Receptor 2 en_US
dc.identifier.citationSrinagarind Medical Journal (SMJ); Vol. 21 No. 4 October - December 2006; 343-351en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/133234
dc.language.isoen_USen_US
dc.publisherFaculty of Medicine, Khon Kaen Universityen_US
dc.rightsAcademic Affairs, Faculty of Medicine, Khon Kaen University, KhonKaen, Thailanden_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/SMJ/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/SMJ/article/view/1950en_US
dc.titleHormonal Receptors Status of Breast Cancer in Northeastern Thai Women : An Analysis of 241 cases at Srinagarind Hospitalen_US
dc.typeOriginal Articlesen_US
Files
Collections
Srinagarind Medical Journal