Lipid Profile and Prevalence of Dyslipidemia in Pre- and Postmenopausal Women in Yaounde, Cameroon

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dc.contributor.authorGerard, Nkeunenen_US
dc.contributor.authorJudith, Tsafack Takadong Julieen_US
dc.contributor.authorGustave, Simoen_US
dc.contributor.authorTambe, Betrand Ayuken_US
dc.contributor.authorRoger, Ayangma Celestinen_US
dc.contributor.authorBonglavnyuy, Tume Christopheren_US
dc.date.accessioned2020-05-05T07:04:21Z
dc.date.available2020-05-05T07:04:21Z
dc.date.issued2019-05
dc.description.abstractAims: Lipids serve several important physiologic functions like energy homeostasis or biosynthesis of hormone within the human body. The deterioration of lipid metabolism which is favoured by menopause is the source of cardiovascular diseases. This study aimed to determine the plasma lipid profile and dyslipidemia prevalence of some Cameroonian women.Study Design:This was a cross-sectional study.Place and Duration of Study:The enrollment took place at the Yaounde Military Hospital from November 2016 to July 2017.Methodology:To achieve this goal, two sets of 105 postmenopausal and 127 premenopausal participants were enrolled in this study. 5ml of blood were collected on EDTA coated tubes from each participant. Enzymatic methods were used to evaluate total cholesterol, HDL cholesterol and triglyceride, while LDL cholesterol was determined using the Friedewald equation. These biological parameters were used to determine dyslipidemia. Thereafter, they were compared within age and year since menopause subgroups. Results:There was no significant difference in the mean values of total cholesterol, HDL-C, LDL-C as well as triglyceride between premenopausal and postmenopausal women. The mean HDL-C concentration wasstable in the age subgroups while the mean total cholesterol and LDL-C were slightly increasing as postmenopausal participants got older. LDL-C level was significantly higher in women who had been in menopause for more than 15 years. The overall dyslipidemia prevalence was 53%. Dyslipidemia was significantly higher in the subgroup of women who had freshly entered menopause.Conclusion:Even though there was no change in the mean concentration of the plasma lipid parameters, of pre-and postmenopausal participants there was a general need to improve their lifestyle in order to reduce dyslipidemia prevalenceen_US
dc.identifier.affiliationsDepartment of Biochemistry, Faculty of Science, University of Dschang, P.O.Box 67, Dschang, Cameroon.en_US
dc.identifier.affiliationsCentre for Food and Nutrition Research, IMPM-MINRESI,P.O.Box 6163 Yaounde, Cameroon.en_US
dc.identifier.affiliationsDepartment of Global Health, Division of Human Nutrition, Stellenbosch University, P.O.Box 241, Cape Town, South Africa.en_US
dc.identifier.affiliationsHôpital Militaire de Yaounde, Cameroonen_US
dc.identifier.citationGerard Nkeunen, Judith Tsafack Takadong Julie, Gustave Simo, Tambe Betrand Ayuk, Roger Ayangma Celestin, Bonglavnyuy Tume Christopher. Lipid Profile and Prevalence of Dyslipidemia in Pre- and Postmenopausal Women in Yaounde, Cameroon . International Journal of Biochemistry Research & Review. 2019 May; 25(4): 1-11en_US
dc.identifier.issn2231-086X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200690
dc.languageenen_US
dc.publisherScience Domain Internationalen_US
dc.relation.issuenumber4en_US
dc.relation.volume25en_US
dc.source.urihttps://doi.org/10.9734/IJBCRR/2019/v25i430081en_US
dc.subjectLipid profileen_US
dc.subjectdyslipidemiaen_US
dc.subjectpremenopausalen_US
dc.subjectpostmenopausalen_US
dc.subjecttotal cholesterolen_US
dc.subjectLDL cholesterolen_US
dc.subjectHDL cholesterolen_US
dc.subjecttriglyceride.en_US
dc.titleLipid Profile and Prevalence of Dyslipidemia in Pre- and Postmenopausal Women in Yaounde, Cameroonen_US
dc.typeJournal Articleen_US
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