Anti-inflammatory properties of 3-methylpyrazolin-5-(4 H)-one-4-[3'-methoxy-4' (2'',3'',4'',6''-tetra-O-acetyl-beta-D-glycopyranosyl]benzylidene (compound IIIA).

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dc.contributor.authorBani, Sen_US
dc.contributor.authorSingh, Sen_US
dc.contributor.authorKaul, Aen_US
dc.contributor.authorSingh, G Ben_US
dc.contributor.authorJain, S Men_US
dc.date.accessioned2009-05-28T14:37:34Z
dc.date.available2009-05-28T14:37:34Z
dc.date.issued1994-08-01en_US
dc.description.abstractOral treatment of compound IIIA exhibited dose related inhibitory action in acute tests of carrageenan, histamine and dextran-induced oedema in rats. Marked inhibitory action of the compound was found when it was administered intraperitoneally in animals. It displayed prominent anti-arthritic activity in chronic tests of adjuvant and formaldehyde-induced arthritis in rats. It prevented the arthritis associated rise in total leucocyte count and erythrocyte sedimentation rate. It also lowered the levels of exudate volume and migration of leucocytes in carrageenan induced pleurisy in rats. It did not exhibit any analgesic, antipyretic or ulcerogenic effect. No mortality was recorded up to 2 g/kg in mice on oral or intraperitoneal treatment over a period of 72 hr.en_US
dc.description.affiliationPharmacology Department, Regional Research Laboratory, Jammu Tawi, India.en_US
dc.identifier.citationBani S, Singh S, Kaul A, Singh GB, Jain SM. Anti-inflammatory properties of 3-methylpyrazolin-5-(4 H)-one-4-[3'-methoxy-4' (2'',3'',4'',6''-tetra-O-acetyl-beta-D-glycopyranosyl]benzylidene (compound IIIA). Indian Journal of Experimental Biology. 1994 Aug; 32(8): 544-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/60951
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnti-Inflammatory Agents, Non-Steroidal --pharmacologyen_US
dc.subject.meshBenzylidene Compounds --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshPyrazolonesen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Inbred Strainsen_US
dc.titleAnti-inflammatory properties of 3-methylpyrazolin-5-(4 H)-one-4-[3'-methoxy-4' (2'',3'',4'',6''-tetra-O-acetyl-beta-D-glycopyranosyl]benzylidene (compound IIIA).en_US
dc.typeJournal Articleen_US
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