Plant-Derived Phenolic Antioxidants and Cancer Prevention

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dc.contributor.authorYuttana Sudjaroenen_US
dc.date.accessioned2011-02-22T08:15:49Z
dc.date.available2011-02-22T08:15:49Z
dc.date.created2010-04-07en_US
dc.date.issued2010-04-07en_US
dc.description.abstractOxidative stress imposed by reactive oxygen species (ROS) plays a crucial role in the pathophysiology associated with cancer and atherosclerosis. The ROS-induced development of cancer involves malignant transformation due to altered gene expression through epigenetic mechanisms as well as DNA mutations. The phenolic antioxidants play an important role in the chemoprevention of diseases especially cancer by reduced excess ROS. This article reviews the classification of major phenolic compound such as, phenolic acids and flavonoids, and the role of phenolic compound in cancer prevention. Future studies are not only elucidated mechanism related to direct antioxidant of phenolic compounds, but also to their ability to bind cellular receptors and transporters and influence gene expression, cell signaling, and cell adhesion.en_US
dc.identifier.citationThai Cancer Journal; Vol.29 No.3 July-September 2009; 126-134en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/132369
dc.language.isoen_USen_US
dc.publisherThai Cancer Journalen_US
dc.rightsNational Cancer Institute of Thailand, Bangkok, Thailanden_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/TCJ/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/TCJ/article/view/3072en_US
dc.titlePlant-Derived Phenolic Antioxidants and Cancer Preventionen_US
dc.typeReview Articleen_US
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