Multidrug Resistant Acinetobacter in Patient with Ventilator Associated Pneumonia: Review Article.

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dc.contributor.authorPatil, Harsha V.en_US
dc.contributor.authorMohite, Shivaji T.en_US
dc.contributor.authorPatil, Virendra C.en_US
dc.date.accessioned2020-11-18T10:25:16Z
dc.date.available2020-11-18T10:25:16Z
dc.date.issued2019-07
dc.description.abstractAcinetobacter is a complex genus, with multiple species. Acinetobacterspecies are the common etiology of nosocomial infections, principally nosocomial pneumonia catheter-associated bacteremia and urinary tract infections. Multidrug Resistant (MDR) Ventilator Associated Pneumonia (VAP) by Acinetobacter spp is increasingly reported from different parts of the world. Transmission of Acinetobacter is aid by the organism's environmental stubbornness, resistance to desiccation and evasion of host immunity. The virulence properties demonstrated by Acinetobacter spp. is primarily by evasion of rapid clearance by the immune system. The capsular polysaccharide is a critical virulence factor that enables immune evasion and lipopolysaccharide triggers septic shock. Conversely, the primary factor of clinical outcome is antibiotic resistance. Acinetobacter spp. has become a discreditable threat for patients on mechanical ventilation. Considering high rate of antibiotic resistance, new preventive and therapeutic alternative pproach for MDR Acinetobacter spp. infections are urgently needed. Worldwide drug esistance in Acinetobacter baumannii is growing. This review article is emphasised on incidence of VAPdue to MDR Acinetobacter, phenotypes, genotypes, associated risk factors and preventive strategyen_US
dc.identifier.affiliationsDepartment of Microbiology, Krishna Institute of Medical Sciences, Malkapur-Karad-415110 (Maharashtra) Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Krishna Institute of Medical Sciences, Malkapur-Karad-415110 (Maharashtra) Indiaen_US
dc.identifier.citationPatil Harsha V., Mohite Shivaji T., Patil Virendra C.. Multidrug Resistant Acinetobacter in Patient with Ventilator Associated Pneumonia: Review Article.. Journal of Krishna Institute of Medical Sciences University. 2019 Jul; 8(3): 1-18en_US
dc.identifier.issn2231-4261
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215611
dc.languageenen_US
dc.publisherKrishna Institute of Medical Sciences Universityen_US
dc.relation.issuenumber3en_US
dc.relation.volume8en_US
dc.source.urihttps://www.jkimsu.com/jkimsu-vol8no3/JKIMSU,%20Vol.%208,%20No.%203,%20July-September%202019%20Page%201-18.pdfen_US
dc.subjectAcinetobacter sppen_US
dc.subjectVentilator Associated Pneumoniaen_US
dc.subjectMechanical Ventilationen_US
dc.subjectMultidrug Resistanten_US
dc.subjectPhenotypesen_US
dc.subjectGenotypesen_US
dc.titleMultidrug Resistant Acinetobacter in Patient with Ventilator Associated Pneumonia: Review Article.en_US
dc.typeJournal Articleen_US
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