Key Factors Influencing Urinary Leak After Percutaneous Nephrolithotomy: Insights And Implications

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dc.contributor.authorReddy, Guddety Sreenivasaen_US
dc.contributor.authorPudakalkatti, Sanjay Ren_US
dc.contributor.authorRamaiah, Keshavamurthyen_US
dc.date.accessioned2025-05-14T09:37:35Z
dc.date.available2025-05-14T09:37:35Z
dc.date.issued2024-12
dc.description.abstractBackground: Percutaneous nephrolithotomy (PCNL) is the standard treatment for large or complex renal stones. Despite its high success rates, complications such as prolonged urinary leakage (PUL) are significant concerns, occurring in 5–15% of cases. This study investigates predictors of PUL following PCNL, focusing on anatomical and procedural factors. A retrospective cohort study of 225 PCNL patients was conducted. Data on demographic,Methods: anatomical (hydronephrosis grade, parenchymal thickness), stone characteristics (volume, location), and procedural factors (surgery time, number of punctures) were analyzed. Urinary leakage was categorized as leakage persisting >24 hours post-nephrostomy removal. Statistical analyses included t-tests, chi-square tests, and multivariate logistic regression. Prolonged urinary leakage occurred in 23 patients (10%). Key predictors included higherResults: hydronephrosis grade (mean: 2.39 vs. 0.98, p<0.001), thinner parenchymal thickness (mean: 15.97 mm vs. 20.11 mm, p<0.001), larger stone volume (mean: 810.14 mm³ vs. 684.56 mm³, p=0.04), and longer surgery time (mean: 92.4 min vs. 81.0 min, p=0.01). Multiple punctures and lower calyceal access were also associated with increased risk. Skin-to- parenchymal length showed no significant correlation with leakage. Higher grades of hydronephrosis,Conclusion: reduced parenchymal thickness, larger stones, prolonged surgery, and multiple punctures are significant predictors of urinary leakage after PCNL. Preoperative imaging and meticulous surgical planning can mitigate these risks.en_US
dc.identifier.affiliationsSenior Resident, Institute of Nephro Urology, Bangaloreen_US
dc.identifier.affiliationsAssociate Professor, Institute of Nephro Urology, Bangaloreen_US
dc.identifier.affiliationsProfessor and Head Of Department, Urology, Institute of Nephro Urology, Bangaloreen_US
dc.identifier.citationReddy Guddety Sreenivasa, Pudakalkatti Sanjay R, Ramaiah Keshavamurthy . Key Factors Influencing Urinary Leak After Percutaneous Nephrolithotomy: Insights And Implications. Paripex - Indian Journal Of Research. 2024 Dec; 13(12): 13-15en_US
dc.identifier.issn2250-1991
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/247889
dc.languageenen_US
dc.publisherINDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCHen_US
dc.relation.issuenumber12en_US
dc.relation.volume13en_US
dc.source.urihttps://www.doi.org/10.36106/paripex/7100425en_US
dc.subjectPercutaneous nephrolithotomyen_US
dc.subjecturinary leakageen_US
dc.subjecthydronephrosisen_US
dc.subjectparenchymal thicknessen_US
dc.subjectkidney stonesen_US
dc.subjectpostoperative complicationsen_US
dc.subjectpredictive factors.en_US
dc.titleKey Factors Influencing Urinary Leak After Percutaneous Nephrolithotomy: Insights And Implicationsen_US
dc.typeJournal Articleen_US
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