Enhancer aided in vitro permeation of atenolol and prazosin hydrochloride through mice skin.

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dc.contributor.authorReddy, L Hen_US
dc.contributor.authorGhosh, Ben_US
dc.date.accessioned2009-05-28T13:26:32Z
dc.date.available2009-05-28T13:26:32Z
dc.date.issued2001-01-15en_US
dc.description.abstractEffect of penetration enhancers were studied on the permeation of antihypertensive drugs prazosin hydrochloride and atenolol through full thickness skin of swiss albino mice. Atenolol was delivered to skin from saturated alcoholic solution containing 5% of 1-decanol and alcohol alone, while prazosin hydrochloride was saturated in dimethyl formamide(DMF, 5% v/v in water) and dimethyl sulfoxide(DMSO, 5% v/v in water). Atenolol permeation was augmented significantly in decanolic solution and also in pure alcohol. In case of prazosin hydrochloride, significant enhancement of permeation was shown by DMSO but not by DMF.en_US
dc.description.affiliationDepartment of Pharmaceutical Technology, V.L. College of Pharmacy, Raichur, India.en_US
dc.identifier.citationReddy LH, Ghosh B. Enhancer aided in vitro permeation of atenolol and prazosin hydrochloride through mice skin. Indian Journal of Experimental Biology. 2001 Jan; 39(1): 47-51en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/59413
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAdministration, Cutaneousen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAtenolol --administration & dosageen_US
dc.subject.meshDimethyl Sulfoxide --administration & dosageen_US
dc.subject.meshDimethylformamide --administration & dosageen_US
dc.subject.meshEthanol --administration & dosageen_US
dc.subject.meshFatty Alcohols --administration & dosageen_US
dc.subject.meshMiceen_US
dc.subject.meshPrazosin --administration & dosageen_US
dc.subject.meshSkin Absorption --drug effectsen_US
dc.titleEnhancer aided in vitro permeation of atenolol and prazosin hydrochloride through mice skin.en_US
dc.typeJournal Articleen_US
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