2-(2,3-dimethylchromon-6-yl) propanoic acid (OVS-103): a potent anti-inflammatory agent.

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dc.contributor.authorBani, Sen_US
dc.contributor.authorSingh, Sen_US
dc.contributor.authorSingh, G Ben_US
dc.contributor.authorSingh, O Ven_US
dc.date.accessioned2009-05-28T11:19:42Z
dc.date.available2009-05-28T11:19:42Z
dc.date.issued1995-11-01en_US
dc.description.abstractThe compound OVS-103 showed dose-dependent anti-inflammatory and anti-arthritic effects in different acute and chronic test models in rats and mice. It produced inhibition of the exudate volume and the migration of leucocytes in the carrageenan induced pleurisy test in rats. OVS-103 showed poor inhibitory effect on granuloma formation induced by cotton pellet and had no anti-pyretic and analgesic property. ALD50 in both rats and mice was more than 2000 mg/kg, p.o. and 1500 mg/kg, i.p.en_US
dc.description.affiliationPharmacology Department, Regional Research Laboratory, Jammu Tawi, India.en_US
dc.identifier.citationBani S, Singh S, Singh GB, Singh OV. 2-(2,3-dimethylchromon-6-yl) propanoic acid (OVS-103): a potent anti-inflammatory agent. Indian Journal of Experimental Biology. 1995 Nov; 33(11): 841-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56561
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnti-Inflammatory Agents, Non-Steroidal --pharmacologyen_US
dc.subject.meshArthritis --drug therapyen_US
dc.subject.meshCapillary Permeability --drug effectsen_US
dc.subject.meshChromones --pharmacologyen_US
dc.subject.meshDisease Models, Animalen_US
dc.subject.meshEdema --drug therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshLethal Dose 50en_US
dc.subject.meshMiceen_US
dc.subject.meshPleurisy --drug therapyen_US
dc.subject.meshPregnancyen_US
dc.subject.meshRatsen_US
dc.subject.meshUterus --drug effectsen_US
dc.title2-(2,3-dimethylchromon-6-yl) propanoic acid (OVS-103): a potent anti-inflammatory agent.en_US
dc.typeJournal Articleen_US
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