EXPRESSION OF CD44 AS A CANCER STEM CELL MARKER IN ORAL CANCER: A META-ANALYSIS STUDY

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dc.contributor.authorSohail, Men_US
dc.contributor.authorCharles, M. Ren_US
dc.contributor.authorAhamad, Een_US
dc.contributor.authorGulfsha, Sahu Den_US
dc.contributor.authorSiddiqui, Z.en_US
dc.date.accessioned2023-07-21T11:32:32Z
dc.date.available2023-07-21T11:32:32Z
dc.date.issued2022-06
dc.description.abstractVarious researches have shown that Cluster of Differentiation 44 (CD44) is one of the valued markers. As it plays an important role in tumor growth and metastasis but studies also suggest it as a cancer stem cell (CSC) marker in oral cancer (OC). Therefore, we aimed to explore association between the expression of CD44 and clinicopathological characteristics along with the OC prognosis.We conducted literature search through PubMed database (till October 22, 2020) to determine and evaluate the clinical and prognostic significance of CD44 expression in OC patients. According to the inclusion criteria we finalized 9 studies with 867 OC cases. We found the positive expression of CD44 in advanced stages was prominently associated with reduced survival rate. Our analysis suggest that higher tumor expression of CD44 may predict poor survival in end staged OC patienten_US
dc.identifier.affiliationsEra's Lucknow Medical College & Hospital, Era University, Sarfarazganj, Lucknow, U. P., India - 226003en_US
dc.identifier.affiliationsResearch Metabolic Unit, Department of Pathologyen_US
dc.identifier.citationSohail M, Charles M. R, Ahamad E, Gulfsha Sahu D, Siddiqui Z.. EXPRESSION OF CD44 AS A CANCER STEM CELL MARKER IN ORAL CANCER: A META-ANALYSIS STUDY. Era's Journal of Medical Research. 2022 Jun; 9(1): 52-59en_US
dc.identifier.issn2394-5222
dc.identifier.issn2348-9839
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220424
dc.languageenen_US
dc.publisherEra's Lucknow Medical College & Hospital, Lucknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume9en_US
dc.source.urihttps://doi.org/10.24041/ejmr2022.08en_US
dc.subjectCancer Stem Cellsen_US
dc.subjectCD44en_US
dc.subjectOral Canceren_US
dc.subjectTumor gradeen_US
dc.subjectPrognosisen_US
dc.titleEXPRESSION OF CD44 AS A CANCER STEM CELL MARKER IN ORAL CANCER: A META-ANALYSIS STUDYen_US
dc.typeJournal Articleen_US
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