Removal of radioactive strontium from the rat by feeding stable strontium.

dc.contributor.authorKshirsagar, S G
dc.date.accessioned2015-07-17T07:31:23Z
dc.date.available2015-07-17T07:31:23Z
dc.date.issued1979-03
dc.description.abstractThe effect of administering the stable isotope of strontium (as phosphate) at different dietary levels to adult rats (fed on a cereal and pulse-based diet containing 0·4% Ca) on the retention of radiostrontium (89Sr) and radiocalcium (45Ca) in the femur and the whole skeleton was studied for a period up to 6 weeks after an intraperitoneal injection of the two radioisotopes. The ability of strontium to remove 89Sr under the above dietary conditions was examined. Feeding Sr at 0·5% or 1% levels for 6 weeks had no effect on the skeletal content of 89Sr or 45Ca while a dietary regimen of 2% Sr (2000 times the normal content), significantly lowered the 89Sr and 45Ca content by about 30% in the femur but not in the whole skeleton. At this Sr level, the urinary excretion of the isotopes increased with a concomitant decrease in their excretion in the faeces. This study underscores the limitations of dietary Sr to mobilise 89Sr from the bones after it is incorporated in the bone mineral.en_US
dc.identifier.citationKshirsagar S G. Removal of radioactive strontium from the rat by feeding stable strontium. Journal of Biosciences. 1979 Mar; 1(1): 99-107.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/159935
dc.language.isoenen_US
dc.source.urihttps://www.ias.ac.in/jarch/jbiosci/1/99-107.pdfen_US
dc.subject89Sr removalen_US
dc.subjectSr feedingen_US
dc.subjectraten_US
dc.subjectcereal and pulse dieten_US
dc.titleRemoval of radioactive strontium from the rat by feeding stable strontium.en_US
dc.typeArticleen_US
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