10-year Survival Rate of Laryngeal Cancer Patients in Maharat Nakhon Ratchsima Hospital

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dc.contributor.authorPhairuch Changprayaden_US
dc.date.accessioned2011-02-16T08:34:41Z
dc.date.available2011-02-16T08:34:41Z
dc.date.created2007-02-04en_US
dc.date.issued2007-02-04en_US
dc.description.abstractPROBLEM/BACKGROUND: Laryngeal cancer is a common malignancy of the head and neck. Favorable prognosis and long-term survival rate is better than other head and neck cancers. OBJECTIVE: To study 5-year and 10-year survival rate of laryngeal cancer patients. RESEARCH DESIGN: A prospective cohort study. SETTING: Department of Otorhinolaryngology, Maharat Nakhon Ratchsima Hospital. MATERIALS and METHOD: Fifteen-year prospective data gathered from medical records of laryngeal cancer patients during January 1992 to December 2006 were analyzed. Data analysis used Kaplan-Meier survival analysis and Cox-regression analysis with significant level at 0.05. RESULTS: Among 248 patients with histologically proven laryngeal cancer (228 males, 20 females) with age range 30-87 (mean 63.49 years); there were supraglottic 38.3%, glottic 25.4%, subglottic 3.2% and transglottic 33.1%. The overall 5-year and 10-year survival rates were 26.1% (95% confidence interval=20.37-32.20) and 19.3% (95% confidence interval=13.93-25.40) respectively. The overall 10-year survival rate by site was 10.9% for supraglottic, 24.0% for glottic, 0% for subglottic and 27.3% for transglottic. The overall 10-year survival rate for stage I through IV was 47.2%, 36.3% 15.2% and 11.5% respectively. CONCLUSIONS: Significant prognostic factors for laryngeal cancer patients are T-stage, N-stage and M-stage. Early diagnosis and treatment are the keys for better survival rates.en_US
dc.identifier.citationBuddhachinaraj Medical Journal; Vol.24 No.3 September-December 2007; 287-295en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/130374
dc.language.isoen_USen_US
dc.publisherBuddhachinaraj Medical Journalen_US
dc.rightsBuddhachinaraj Medical Journalen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/BMJ/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/BMJ/article/view/1226en_US
dc.title10-year Survival Rate of Laryngeal Cancer Patients in Maharat Nakhon Ratchsima Hospitalen_US
dc.typeOriginal Articlesen_US
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