Biochemical Factors associated with Breast Cancer in Bangladeshi Women.
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Date
2013
Journal Title
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Volume Title
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Abstract
Breast Cancer is the commonest maligrancy in woment. A study was carried out in the
Department of Biochemistry, Dhaka Medical College to investigate some of the
biochemical features that are associated with breast cancer occurring in Bangladeshi
women. Thirty diagnosed breast cancer patients and thirty healthy women were selected. A
questionnaire was used for collecting information regarding age, family history, physical
activity and exercise, BMI, diet, smoking, alcohol abuse, addiction, details of menstrual
and obstetric history, breast-feeding, parity, use of contraceptives and HRT. Blood samples
were collected and tested for fasting lipid profiles, serum estrogen and progesterone. The
study has revealed that high levels of serum total cholesterol (P<0.05), TAG (P<0.05),
LDL-C (P<0.05) and low level of serum and HDL-C (P<0.05) were found to be
associated with breast cancer. The study further reveals that blood levels of estrogen
(P<0.05) and progesterone (P<0.05) were found to be lower than that of the controls.
Description
Keywords
Breast cancer, Lipid profile, Estrogen, Progesterone
Citation
Hussain DAS, Ahmed S, Hoque M, Rabbi S M R, Masood S, Shafi T, Parvin T, Chaudhury H S. Biochemical Factors associated with Breast Cancer in Bangladeshi Women. Bangladesh Journal of Medical Biochemistry. 2013; 6(2): 58-62.