Mystery of the Treatment of Syphilis

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dc.contributor.authorRajashekar, TSen_US
dc.contributor.authorSuresh Kumar, Ken_US
dc.contributor.authorMeghana, Een_US
dc.contributor.authorPavithra, TRen_US
dc.contributor.authorDeepthi Chowdary, Yen_US
dc.contributor.authorHanumanthayya, K.en_US
dc.date.accessioned2024-11-30T11:33:20Z
dc.date.available2024-11-30T11:33:20Z
dc.date.issued2023-04
dc.description.abstractSyphilis is the commonest sexually transmitted disease (STD) affecting humans globally. On 12.10.1492, Christopher Columbus with his crew landed in Haiti (America) and returned to Spain (Europe) on 15th March 1493. Historians believe that, he and his crew members spread the disease syphilis in Europe, which he and his crew members had contracted in Haiti. The migration of people due to war (soldiers and mercenaries), merchants and slave trade contributed to the rapid spread of the disease and it became a pandemic. Initially, syphilis was highly contagious and virulent, affecting millions of people with very high mortality. Hence, the physicians of that time left no stone unturned for finding a cure. They tried mostly ineffective and harmful methods to treat syphilis. The drugs proved to be more harmful than curative. The fatality due to drugs itself was very significant. Alexander Fleming, a Scottish physician discovered penicillin in 1928 as a crude extract from Penicillium rubens. Eagle H and his coworkers in 1940, found that, penicillin at a relatively low dosage used over a prolonged period of four weeks cured syphilis. The discovery of penicillin enabled to transform a disease with high mortality to a manageable disease.en_US
dc.identifier.affiliationsSri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, Indiaen_US
dc.identifier.affiliationsSri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, Indiaen_US
dc.identifier.affiliationsSri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, Indiaen_US
dc.identifier.affiliationsSri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, Indiaen_US
dc.identifier.affiliationsSri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, Indiaen_US
dc.identifier.affiliationsSri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, Indiaen_US
dc.identifier.citationRajashekar TS, Suresh Kumar K, Meghana E, Pavithra TR, Deepthi Chowdary Y, Hanumanthayya K.. Mystery of the Treatment of Syphilis. Journal of Clinical and Biomedical Sciences. 2023 Apr; 13(2): 34-36en_US
dc.identifier.issn2319-2453
dc.identifier.issn2231-4180
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/238031
dc.languageenen_US
dc.publisherSri Devaraj Urs Academy of Higher Educationen_US
dc.relation.issuenumber2en_US
dc.relation.volume13en_US
dc.source.urihttps://doi.org/10.58739/jcbs/v13i2.22.117en_US
dc.subjectSyphilisen_US
dc.subjectTreponema pallidumen_US
dc.subjectInfectious diseaseen_US
dc.titleMystery of the Treatment of Syphilisen_US
dc.typeJournal Articleen_US
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