Serum phosphorus levels as a predictor and severity marker for mechanical ventilation in adults versus elderly patients – A cross-sectional study

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dc.contributor.authorAmbali, APen_US
dc.contributor.authorTomar, Pen_US
dc.contributor.authorShivanand, LKen_US
dc.date.accessioned2024-12-07T11:14:10Z
dc.date.available2024-12-07T11:14:10Z
dc.date.issued2024-07
dc.description.abstractObjectives: Mechanical ventilation (MV) is a supportive therapy for patients with acute respiratory failure. Studies have shown direct relationship between serum phosphorus on admission and risk of respiratory failure requiring MV. This study aims to determine admission serum phosphorus level’s ability to predict severity in 64 mechanically ventilated patients among two groups: Group A was designated to adults (<60 years of age) and Group B to elderly (60 years or older) admitted to the critical care unit (CCU). Study Design: It is a cross-sectional study. Material and Methods: Data were collected from 64 adults admitted to CCU. The Sequential Organ Failure Assessment (SOFA) score and serum Phosphorus level on admission were assessed. Patients with Diabetic Ketoacidosis, Head Trauma, Renal Failure, Hyper or Hypoparathyroidism, Leukaemia, and Lymphoma were excluded. Results: The study had 32 subjects in each group. The commonest indication for mechanical ventilation was Poisoning (31.25%) in Group A and Cerebrovascular Accident (34.37%) in Group B. The common complication among the study group was ventilator- associated pneumonia (14.06%). Out of 64 patients requiring mechanical ventilation, nine patients had hypophosphatemia, and eighteen had hyperphosphatemia. In the case of hypophosphatemia, 100% and in hyperphosphatemia, 55.5% mortality was observed. Conclusion: Altered serum phosphorus levels on admission can be a potential indicator for requiring MV and mortality. Both hypophosphatemia and hyperphosphatemia are potential risk factors for the development of respiratory failure. Also, age-related variation in phosphorus levels has not shown any association with the outcome.en_US
dc.identifier.affiliationsDepartment of Geriatrics, Bijapur Lingayat District Education Deemed to be University, Vijayapura, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Bijapur Lingayat District Education Deemed to be University, Vijayapura, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Anesthesia, Bijapur Lingayat District Education Deemed to be University, Vijayapura, Karnataka, Indiaen_US
dc.identifier.citationAmbali AP, Tomar P, Shivanand LK . Serum phosphorus levels as a predictor and severity marker for mechanical ventilation in adults versus elderly patients – A cross-sectional study . Annals of the National Academy of Medical Sciences (India). 2024 Jul; 60(3): 201-205en_US
dc.identifier.issn0379-038X
dc.identifier.issn2454-5635
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/241065
dc.languageenen_US
dc.publisherNational Academy of Medical Sciencesen_US
dc.relation.issuenumber3en_US
dc.relation.volume60en_US
dc.source.urihttps://dx.doi.org/10.25259/ANAMS_1071_2023en_US
dc.subjectMechanical ventilationen_US
dc.subjectMortalityen_US
dc.subjectSerum phosphorusen_US
dc.subjectSOFA scoreen_US
dc.subjectAdultsen_US
dc.subjectElderlyen_US
dc.titleSerum phosphorus levels as a predictor and severity marker for mechanical ventilation in adults versus elderly patients – A cross-sectional studyen_US
dc.typeJournal Articleen_US
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