Development And Validation Of Uv-Visible Spectrophotmetric Method For The Simultaneous Estimation Of Emtricitabine And Tenofovir Alafenamide In Bulk And Tablet Dosage Form

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dc.contributor.authorEBIN, CJen_US
dc.contributor.authorSHEEJA, VKen_US
dc.date.accessioned2020-09-24T07:33:49Z
dc.date.available2020-09-24T07:33:49Z
dc.date.issued2019-06
dc.description.abstractAbstract: A simple, rapid, accurate and economical method has been developed for thesimultaneous estimation of Emtricitabine and Tenofovir Alafenamide in tablet dosage form.The linearity of the method was found to be in the range of 10.8µg/ml- 12.8µg/ml forTenofovir Alafenamide and 86.4µg/ml-102.4µg/ml for Emtricitabine. From the developedmethod the drugs showed maximum absorbance at 263 and 281nm for Tenofovir Alafenamideand Emtricitabine respectively. The percentage purity of the drugs was found as 96.8 and97.6%w/w for Tenofovir Alafenamide and Emtricitabine respectively. The method was alsofound to be accurate, precise, robust and rugged. The limit of detection and the limit ofquantification were found to be 0.234µg/ml and 0.710µg/ml for Tenofovir Alafenamide and2.25µg/ml and 6.83µg/ml for Emtricitabine respectively..en_US
dc.identifier.affiliationsDepartment of Pharmaceutical Analysis, Grace College Of Pharmacy, Kodunthirapully, Palakkad, Kerala, 678004, India.en_US
dc.identifier.citationEbin Cj, Sheeja Vk. Development And Validation Of Uv-Visible Spectrophotmetric Method For The Simultaneous Estimation Of Emtricitabine And Tenofovir Alafenamide In Bulk And Tablet Dosage Form. International Journal of Pharmaceutical Research and Bioscience (IJPRBS). 2019 Jun; 8(3): 1-9en_US
dc.identifier.issn2277-8713
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203812
dc.languageenen_US
dc.publisherBimonthly published online Journalen_US
dc.relation.issuenumber3en_US
dc.relation.volume8en_US
dc.source.urihttps://www.ijprbs.com/issuedocs/2019/6/IJPRBS%201473.pdfen_US
dc.subjectTenofovir Alafenamide (TEN)en_US
dc.subjectEmtricitabine (EMT)en_US
dc.subjectUV-Visible spectroscopyen_US
dc.titleDevelopment And Validation Of Uv-Visible Spectrophotmetric Method For The Simultaneous Estimation Of Emtricitabine And Tenofovir Alafenamide In Bulk And Tablet Dosage Formen_US
dc.typeJournal Articleen_US
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