Efficacy of Intravenous Lignocaine 2% Versus Oropharyngeal Topical 10% Xylocaine Spray Before Induction of Anaesthesia in Attenuating the Pressor Response to Direct Lryngoscopy and Endotracheal Intubation

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dc.contributor.authorMahajan, Artien_US
dc.contributor.authorGupta, Akhil Kumaren_US
dc.contributor.authorGulati, Sen_US
dc.contributor.authorGupta, Sunainaen_US
dc.date.accessioned2020-10-16T09:00:38Z
dc.date.available2020-10-16T09:00:38Z
dc.date.issued2019-01
dc.description.abstractThe current Study was done to compare the efficacy of intravenous lignocaine 2% versus oropharyngeal topical 10% xylocaine spray before induction of anaesthesia in attenuating the pressor response to direct laryngoscopy and endotracheal intubation. A total of 60 patients were divided randomly into two groups of 30 patients each. Group I received intravenous lignocaine 2% @ 1.5 mg/kg. Group II received topical 10% xylocaine spray @ 1.5 mg/kg body weight just before induction of anaesthesia. All hemodynamic parameters were measured immediately after laryngoscopy and intubation and at 1, 3, 5 minutes after laryngoscopy and intubation in both the groups. Mean values of haemodynamic parameters in Group I increased after intubation and then started declining but did not reach the baseline even at 5 minutes. In Group II all mean values of haemodynamic parameters increased after intubation and then started declining to almost baseline at 5 minutes. The differences in mean values of haemodynamic between the two groups immediately after intubation and at 1, 3 and 5 minutes thereafter were statistically highly significant (p<0.001). Oropharyngeal topical xylocaine 10% when applied before induction of general anaesthesia is more effective method for attenuating the pressor response to direct laryngoscopy and endotracheal intubation when compared to intravenous lignocaine 2%en_US
dc.identifier.affiliationsDepartment of Anaesthesiology and Intensive Care, Government Medical College, Jammuen_US
dc.identifier.citationMahajan Arti, Gupta Akhil Kumar, Gulati S, Gupta Sunaina. Efficacy of Intravenous Lignocaine 2% Versus Oropharyngeal Topical 10% Xylocaine Spray Before Induction of Anaesthesia in Attenuating the Pressor Response to Direct Lryngoscopy and Endotracheal Intubation. JK Science Journal of Medical Education and Research. 2019 Jan; 2019 Jan: 3-7en_US
dc.identifier.issn0972-1177
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/210970
dc.languageenen_US
dc.publisherJK Scienceen_US
dc.relation.issuenumber1en_US
dc.relation.volume21en_US
dc.source.urihttps://www.jkscience.org/archives/volume211/2-Original%20Article.pdfen_US
dc.subjectLaryngoscopyen_US
dc.subjectEndotracheal intubationen_US
dc.subjectIntravenous lignocaine 2%en_US
dc.subjectOropharyngeal Topical 10% xylocaineen_US
dc.subjectPressor Responseen_US
dc.titleEfficacy of Intravenous Lignocaine 2% Versus Oropharyngeal Topical 10% Xylocaine Spray Before Induction of Anaesthesia in Attenuating the Pressor Response to Direct Lryngoscopy and Endotracheal Intubationen_US
dc.typeJournal Articleen_US
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