Staphylococcus Aureus MSSA Yet Disseminated

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dc.contributor.authorPrakash, Ashwinien_US
dc.contributor.authorH, Haroonen_US
dc.contributor.authorShetty, Aakankshaen_US
dc.date.accessioned2024-12-02T12:00:20Z
dc.date.available2024-12-02T12:00:20Z
dc.date.issued2024-11
dc.description.abstractIntroduction: Staphylococcus Aureus Bacteremia (SAB) is a major cause of bloodstream infections, associated with high morbidity and mortality. Methicillin-Sensitive Staphylococcus aureus (MSSA) can cause invasive and disseminated infections, particularly in patients with comorbidities. Managing disseminated MSSA is challenging due to its potential to form abscesses, recurrent bacteremia, and involve multiple organ systems. We report the case of a 44-Case Report: year-old male with poorly controlled Type 2 Diabetes Mellitus and recurrent MSSA bacteremia. The patient initially presented with fever, anorexia, and significant weight loss. Imaging and laboratory findings revealed Pyelonephritis with microabscesses and Diabetic Ketoacidosis. During subsequent admissions, he presented with a right foot ulcer, Osteomyelitis, and recurrent urinary tract infections (UTIs), requiring multiple hospitalizations. After blood and urine cultures confirmed MSSA, broad-spectrum antibiotics were initiated and later tailored to Cloxacillin and Clindamycin. Bilateral Double-J stenting was performed to relieve Hydroureteronephrosis, and surgical debridement of the foot ulcer. The patient showed clinical improvement after a six-week antibiotic course. This case underscores theDiscussion: challenges in managing disseminated MSSA infections in a diabetic patient with recurrent hospitalizations. Infections such as pyelonephritis and osteomyelitis often require prolonged antibiotic therapy, source control through surgical intervention, and close monitoring to prevent recurrence. Diabetic patients are at an increased risk of invasive MSSA due to compromised immunity, which requires a multifaceted approach for successful management. EffectiveConclusion: management of disseminated MSSA infections in high-risk patients requires timely diagnosis, comprehensive antimicrobial therapy, and vigilant follow-up. Involvement of infectious disease specialists and adherence to antibiotic protocols improve outcomes, particularly in patients with comorbidities.en_US
dc.identifier.affiliationsDepartment Of Internal Medicine KMC Hospital, Dr B.R Ambedkar Circle, Mangalore, Karnataka Indiaen_US
dc.identifier.affiliationsDepartment Of Internal Medicine Kasturba Medical College Mangalore, Manipal Academy Of Higher Education, Manipal, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment Of Internal Medicine KMC Hospital, Dr. B. R. Ambedkar Circle, Mangalore, Karnataka, Indiaen_US
dc.identifier.citationPrakash Ashwini, H Haroon, Shetty Aakanksha . Staphylococcus Aureus MSSA Yet Disseminated . Paripex - Indian Journal Of Research. 2024 Nov; 13(11): 1-4en_US
dc.identifier.issn2250-1991
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/240718
dc.languageenen_US
dc.publisherINDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCHen_US
dc.relation.issuenumber11en_US
dc.relation.volume13en_US
dc.source.urihttps://www.doi.org/10.36106/paripexen_US
dc.subjectStaphylococcus aureus bacteremiaen_US
dc.subjectDisseminated Methicillin- Sensitive Staphylococcus aureusen_US
dc.subjectdiabetes mellitusen_US
dc.subjectpyelonephritisen_US
dc.subjectosteomyelitisen_US
dc.subjectrecurrent infectionsen_US
dc.subjectabscess formationen_US
dc.subjectantibiotic therapyen_US
dc.titleStaphylococcus Aureus MSSA Yet Disseminateden_US
dc.typeJournal Articleen_US
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