Antimicrobial and wound healing studies on the extracts of the medicinal plant cocculus hirsutus (linn).
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Date
2012-04
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Abstract
The antimicrobial activity of methanol and aqueous extracts of the medicinal plant
Cocculus hirsutus was studied using E.coli, Vibrio cholerae, Pseudomonas fluorescence, Klebsiella
pneumoniae and Staphylococcus aureus ,Candida gillermontii,Tricophyton rubrum,Tricophyton
tansuans,Aspergillus ochraceus,Candida albicans and Rodatrula sp as test micoorganisms.The methanol
extract of the plant was found to be more effective against Vibrio cholera(18) and Staphylococcus
aureus(17mm) and in the mean time the aqueous extract was found to be more effective against Vibrio
cholera(13) and Klebsiella pneumonia (14mm).Both methanol and aqueous extract of this plant was found
with no fungal activity against fungal pathogens. Phytochemical screening of the methanol extract of
Cocculus hirsutus revealed the presence of alkaloids, steroids, tannins and saponins, which suggests may
be responsible for antimicrobial activity. The wound healing potencial of this plant was found to be
comparably better than that of the commercial antibiotic Neomycin.
Description
Keywords
Antimicrobial activity, Leaves, Well cut method, Clinical pathogens, Phytoconstituents
Citation
Kalirajan A, Michael J Savarimuthu, Singh A J A Ranjit, Padmalatha C. Antimicrobial and wound healing studies on the extracts of the medicinal plant cocculus hirsutus (linn). International Journal of Applied Biology and Pharmaceutical Technology. 2012 Apr-Jun; 3(2): 63-67.