Effect of maternal iron deficiency on GABA shunt pathway of developing rat brain.

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dc.contributor.authorTaneja, Ven_US
dc.contributor.authorMishra, K Pen_US
dc.contributor.authorAgarwal, K Nen_US
dc.date.accessioned2009-05-28T16:05:50Z
dc.date.available2009-05-28T16:05:50Z
dc.date.issued1990-05-01en_US
dc.description.abstractIron deficiency during pregnancy and lactation (35 mg iron/kg diet) produced a significant reduction in liver nonheme iron in dams as well as in fetus and young ones. The body, liver and brain weights of fetus, new-born, and developing pups remained unaffected. However, the body weight and PCV were reduced only in 21-day-old pups. The enzyme activities of GDH, GAD, GABA-transaminase, and NAD(+)-linked ICDH were reduced in 14 and 21-day-old pups. The enzyme activities of NADP(+)-linked ICDH activities remained unaffected in the fetus and developing pups brain. Maternal rehabilitation on iron sufficient diet for 1 week from day 14 to 21 of lactation period did not reverse these changes. The maternal iron deficiency during lactation period alone did not cause any alteration in all parameters assayed, however, there was a reduction in liver non-heme iron of pups on days 14 and 21.en_US
dc.description.affiliationDepartment of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi, India.en_US
dc.identifier.citationTaneja V, Mishra KP, Agarwal KN. Effect of maternal iron deficiency on GABA shunt pathway of developing rat brain. Indian Journal of Experimental Biology. 1990 May; 28(5): 466-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/62803
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBrain --growth & developmenten_US
dc.subject.meshFemaleen_US
dc.subject.meshIron --deficiencyen_US
dc.subject.meshLactationen_US
dc.subject.meshMaternal-Fetal Exchangeen_US
dc.subject.meshPregnancyen_US
dc.subject.meshRatsen_US
dc.subject.meshgamma-Aminobutyric Acid --metabolismen_US
dc.titleEffect of maternal iron deficiency on GABA shunt pathway of developing rat brain.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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