Coagulation Impairment in Type 2 Diabetes Mellitus.
Loading...
Date
2015-06
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background: Complication of diabetes mellitus (DM) includes coagulation impairment.
Hypercoagulable state in patient with DM may accelerate thromboembolic risk for cardiovascular
disease (CVD). Objective: To assess Prothrombin Time and Activated Partial Thromboplastin Time in
type 2 diabetes mellitus for observing their coagubility status. Methods: This cross sectional study
was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2013 to
June 2014. One hundred male patients with type 2 diabetes mellitus aged 40-60 years and one hundred
age, BMI matched healthy subjects were included as control in this study. Patients were selected from
BIRDEM, Dhaka. Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT) were estimated
by auto analyzer. For statistical analysis unpaired student’t test was used. Results: In this study PT
and APTT were significantly (P<0.001) lower in diabetes mellitus than those of control group.
Conclusion: From this study, it may be concluded that diabetic patients are prone to develop coagulation
impairment.
Description
Keywords
Prothromin time, Activated partial thromboplastin time, cardiovascular disease, diabetes mellitus
Citation
Karim Fayeza, Akter Qazi Shamima, Jahan Shamima, Khanom Afruza, Haque Samira, Yeasmin Tania, Siddika Tashfia, Sinha Susmita. Coagulation Impairment in Type 2 Diabetes Mellitus. Journal of Bangladesh Society of Physiologists. 2015 June; 10(1): 26-29.