Increased apoptosis in AK-5 tumor cells after transfection with wild type p53 gene.

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dc.contributor.authorPardhasaradhi, B Ven_US
dc.contributor.authorKhar, Aen_US
dc.date.accessioned2009-05-28T11:04:42Z
dc.date.available2009-05-28T11:04:42Z
dc.date.issued1996-10-01en_US
dc.description.abstractAK-5 tumor cell death is mediated through necrosis and apoptosis. The apoptotic activity in AK-5 cells has been studied after introduction of wild-type p53 gene. Apoptotic activity both in vitro and in vivo is significantly increased in p53 transfected cells. Similarly there is fragmentation of tumor cell DNA after undergoing apoptosis. These observations suggest an active participation of p53 in inducing apoptosis in AK-5 tumor cells.en_US
dc.description.affiliationCentre for Cellular and Molecular Biology, Hyderabad, India.en_US
dc.identifier.citationPardhasaradhi BV, Khar A. Increased apoptosis in AK-5 tumor cells after transfection with wild type p53 gene. Indian Journal of Experimental Biology. 1996 Oct; 34(10): 945-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56208
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshApoptosis --geneticsen_US
dc.subject.meshGenes, p53en_US
dc.subject.meshHistiocytoma, Benign Fibrous --geneticsen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshTransfectionen_US
dc.titleIncreased apoptosis in AK-5 tumor cells after transfection with wild type p53 gene.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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