A comprehensive review on acarbose in glycaemia control: current insights and future prospects

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dc.contributor.authorSingh, ANen_US
dc.contributor.authorPatel, MIen_US
dc.contributor.authorShah, KRen_US
dc.contributor.authorUnadkat, Ven_US
dc.date.accessioned2025-06-18T11:23:11Z
dc.date.available2025-06-18T11:23:11Z
dc.date.issued2025-06
dc.description.abstractThis comprehensive review examines the part of acarbose in glycaemic control, particularly in managing Glycaemic control among type 1, and also type 2 diabetes mellitus (T2DM) along with gestational diabetes mellitus (GDM). Acarbose, an alpha-glucosidase inhibitor, works by delaying carbohydrate (carb.) digestion in the small intestine (SI), thereby preventing sharp postprandial blood glucose (BG) spikes. This mechanism of action is crucial for maintaining stable glycaemic levels (lvl.s) and reducing HbA1c, which is vital in preventing long-term diabetes complications. The review highlights recent clinical studies that demonstrate acarbose’s efficacy and safety profile, including its minimal systemic absorption and tolerability across diverse patient populations. Additionally, it explores the potential of acarbose in combination therapy with other antidiabetic agents (ADAs), emphasizing its complementary effects in enhancing overall glycaemic control. Furthermore, the discussion addresses emerging trends, ongoing research, and future directions for acarbose in diabetes management, underscoring its significance as a valuable tool in therapeutic strategies aimed at improving patient outcomes.en_US
dc.identifier.affiliationsDepartment of Internal Medicine and Diabetes, Manjalpur Hospital, Tulsidham Char Rasta, Manjalpur, Vadodara, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Veer Narmad South Gujarat University, Surat, Gujarat, Indiaen_US
dc.identifier.affiliationsPooja Nursing Home, Palace Road, Vadodara, Gujarat, Indiaen_US
dc.identifier.affiliationsYashvee Diabetes Clinic, Vadodara, Gujarat, Indiaen_US
dc.identifier.citationSingh AN, Patel MI, Shah KR, Unadkat V. A comprehensive review on acarbose in glycaemia control: current insights and future prospects. International Journal of Basic & Clinical Pharmacology. 2025 Jun; 14(3): 428-436en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/248649
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume14en_US
dc.source.urihttps://doi.org/10.18203/2319-2003.ijbcp20251072en_US
dc.subjectAcarboseen_US
dc.subjectGlycaemic controlen_US
dc.subjectType 2 diabetes mellitusen_US
dc.subjectPostprandial hyperglycaemiaen_US
dc.subjectAlpha-glucosidase inhibitoren_US
dc.subjectHbA1cen_US
dc.subjectCombination therapyen_US
dc.subjectDiabetes managementen_US
dc.titleA comprehensive review on acarbose in glycaemia control: current insights and future prospectsen_US
dc.typeJournal Articleen_US
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