Efficacy of Oral Tranexamic Acid in the Treatment of Melasma: A Pilot Study

Simple item page
dc.contributor.authorKakru, Shafia Nen_US
dc.contributor.authorRaihan, Mden_US
dc.contributor.authorBeg, Mirza Aumiren_US
dc.contributor.authorKakroo, Basiten_US
dc.date.accessioned2019-11-16T07:27:19Z
dc.date.available2019-11-16T07:27:19Z
dc.date.issued2017-10
dc.description.abstractBackground: Melasma a common skin pigmentary disorder poses a great challenge to clinicians due to unsatisfactory results and high recurrence rate. Many treatment modalities have been tried by clinicians without significant improvement in the lesion. Methods: This cross sectional study was done on 90 patients including both male and female and were diagnosed with moderate to severe melasma. TA 250 mg (thyrodin) bid for six months was prescribed along with topical sunscreen. Digital photography was performed at the first visit and at subsequent visits. The effects of treatment were evaluated by two dermatologists independently. Results were assed clinically and photographically. Result: 90 patients with moderate to severe melasma were enrolled in the study. The average age was 36 years. 44patients (48.8%) had good improvement, 25 patients (27.7%) had excellent improvement and 17 patients (18.8%) had fair improvement and 4 patients (4.4%) had no improvement. Three patients complained about gastric upset. None of the patients had serious systemic side effects, only few had oligomenorrhoea, palpitation. Patient’s satisfaction was similarly noted. Conclusion: oral administration of TA is effective and safe treatment for melasma.en_US
dc.identifier.affiliationsLecturer, Department of Dermatology, Venerology and Leprosy, Hamdard Institute of Medical Sciences and research, Delhi, India.en_US
dc.identifier.affiliationsAssociate Professor, Department of Dermatology, Venerology and Leprosy, Hamdard Institute of Medical Sciences and research, Delhi, Indiaen_US
dc.identifier.affiliationsAssisant professor, Department of Pedodontics, Suda Rustagi College of Dental Sciences & Research, Faridabad, Haryana.en_US
dc.identifier.affiliationsBasit Kakroo, Medical student at the University Of East Anglia, Norwich Medical school.en_US
dc.identifier.citationKakru Shafia N, Raihan Md, Beg Mirza Aumir, Kakroo Basit. Efficacy of Oral Tranexamic Acid in the Treatment of Melasma: A Pilot Study. International Archives of BioMedical and Clinical Research. 2017 Oct-Dec; 3(4): 93-96en_US
dc.identifier.issn2454-9894
dc.identifier.issn2454-9886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/184485
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber4en_US
dc.relation.volume3en_US
dc.source.urihttps://doi.org/10.21276/iabcr.2017.3.4.23en_US
dc.subjectMelasmaen_US
dc.subjectOral Tranexamic Aciden_US
dc.titleEfficacy of Oral Tranexamic Acid in the Treatment of Melasma: A Pilot Studyen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
iabcr2017v3n4p93.pdf
Size:
2.15 MB
Format:
Adobe Portable Document Format
Download
Collections
International Archives of BioMedical and Clinical Research