Potentiality of a new compound for in vitro differentiation between halophilic and non-halophilic vibrios.

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dc.contributor.authorRay, Ren_US
dc.contributor.authorDas, A Ken_US
dc.contributor.authorDutta, N Ken_US
dc.contributor.authorChakrabarty, A Nen_US
dc.contributor.authorChaudhuri, B Nen_US
dc.contributor.authorSeth, Sen_US
dc.contributor.authorDastidar, Sujata Gen_US
dc.date.accessioned2009-05-28T13:22:26Z
dc.date.available2009-05-28T13:22:26Z
dc.date.issued2002-02-08en_US
dc.description.abstractSensitivity of 21 halophilic vibrios and 16 clinical isolates of non-halophilic vibrios was determined against a new possible antivibrio agent, a pyrimidine analogue, 4, 6-dimethylpyrimidine -2-thiol (4,6-DMPT). It appeared to be a vibriocidal agent, having a mean MIC and MBC of 32 microg/ml for halophilic strains and 64 microg/ml for non-halophilic strains and an LD50 of 300 mg/Kg body weight of mice. Thus, 4,6-DMPT may help an in vitro distinction between halophilic and non-halophilic vibrios. Sensitivity of these strains was also studied with respect to pteridine, crystal violet and Tween 80 hydrolysis as further markers distinguishing between these 2 groups which could also be differentiated by their growth on TCBS or/and CLED media.en_US
dc.description.affiliationDepartment of Medical Microbiology & Parasitology, University College of Medicine, Kolkata 700 020, India.en_US
dc.identifier.citationRay R, Das AK, Dutta NK, Chakrabarty AN, Chaudhuri BN, Seth S, Dastidar SG. Potentiality of a new compound for in vitro differentiation between halophilic and non-halophilic vibrios. Indian Journal of Experimental Biology. 2002 Feb; 40(2): 220-2en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/59323
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnti-Bacterial Agents --pharmacologyen_US
dc.subject.meshAnti-Infective Agents, Local --pharmacologyen_US
dc.subject.meshGentian Violet --pharmacologyen_US
dc.subject.meshHydrolysisen_US
dc.subject.meshMiceen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshPolysorbates --pharmacologyen_US
dc.subject.meshPteridines --pharmacologyen_US
dc.subject.meshPyrimidines --pharmacologyen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshSurface-Active Agents --pharmacologyen_US
dc.subject.meshVibrio cholerae --classificationen_US
dc.subject.meshVibrio parahaemolyticus --classificationen_US
dc.titlePotentiality of a new compound for in vitro differentiation between halophilic and non-halophilic vibrios.en_US
dc.typeJournal Articleen_US
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