The In vitro Effects on Platelet Functions and Coagulation of Different Prime Solutions Used in Cardiopulmonary by Pass.

Simple item page
dc.contributor.authorBozoglan, Orhan
dc.contributor.authorSerhatlıoglu, Faruk
dc.contributor.authorKahraman, Cemal
dc.date.accessioned2017-01-17T09:12:19Z
dc.date.available2017-01-17T09:12:19Z
dc.date.issued2016
dc.description.abstractPurpose: To investigate the in vitro effect of human albumin (HA) and fresh frozen plasma (FFP) added to prime solution on platelet functions and coagulation in patients undergoing cardiopulmonary bypass (CPB) surgery. Methods: Sixty consecutive patients receiving elective cardiopulmonary bypass with open heart surgery were enrolled in the study. Patients were divided into three equal groups. Group 1: with 2 units of fresh frozen plasma added to prime solution. Group 2: With 100 cc 25% human albumins added to prime solution. Group 3: (control group) with no FFP or HA added to prime solution. PFA-100 platelet function analyzer and platelet aggregation tests were investigated pre-induction, during and after CPB and on the 1st day postoperatively. Results: Postoperative drainage was significantly higher in groups 2 and 3 compared to Group 1 (p<0.01). The compromise in platelet functions in groups 1 and 2 improved, while in Group 3 preoperative values were not attained at the end of the 1st day postoperatively. There was a significant difference between groups 2 and 3 in terms of erythrocyte suspension (ES) used in intensive care (p<0.01). Greater hemorrhage occurred in the postoperative period in Group 3 and more ES was used. In addition, lengths of stay in intensive care differed significantly between groups 2 and 3 (p<0.01). Conclusion: FFP used in CPB causes reduced drainage in the postoperative period and necessitates less use of blood and blood products.en_US
dc.identifier.citationBozoglan Orhan, Serhatlıoglu Faruk, Kahraman Cemal. The In vitro Effects on Platelet Functions and Coagulation of Different Prime Solutions Used in Cardiopulmonary by Pass.British Journal of Medicine and Medical Research. 2016; 11(1): 1-6.en_US
dc.identifier.issn2231-0614
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/181902
dc.language.isoenen_US
dc.source.urihttps://www.sciencedomain.org/abstract/11464en_US
dc.subjectCardiopulmonary bypassen_US
dc.subjectfresh frozen plasmaen_US
dc.subjecthuman albuminen_US
dc.subjectplatelet function analyzeren_US
dc.titleThe In vitro Effects on Platelet Functions and Coagulation of Different Prime Solutions Used in Cardiopulmonary by Pass.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
bjmmr2016v11n1p1-6.pdf
Size:
103.75 KB
Format:
Adobe Portable Document Format
Description:
Original research article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal of Advances in Medicine and Medical Research