Creatine Supplementation in Wistar Rats Submitted to Physical Tests of Swimming: Evaluation of the Physiological Effects through Raman Spectroscopy.
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Date
2011-04
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Abstract
Creatine is a nitrogenous organic acid that naturally occurs in vertebrates. This
compound is associated to energy supply to muscles, being that its biological synthesis
occurs mainly in liver and is related to the aminoacids glycine, arginine and ornitine.
Several studies have shown the benefits of creatine supplementation, such as higher
muscle power, increased fat-free mass, and strength in healthy subjects. Besides, it can
be applied as therapeutic agent for some diseases. In this work, the physical condition
of Wistar rats that received creatine supplementation is compared with individuals
without any supplementation. For this evaluation, swimming tests were developed in
order to elucidate the physical condition of animals in different nutritional conditions.
Indeed, swimming is considered one of the most complete exercises, since the practice
of this physical activity involves great increase in the aerobic and anaerobic capability.
Description
Keywords
Creatine supplementation, swimming, Raman Spectroscopy, Wistar rats, physical tests, physiological effects
Citation
Miranda Humberto, Novaes Jefferson da Silva, Souza Renato Aparecido de, Jerônimo Diego Pereira, Ribeiro Wellington, Tosato Maira Gaspar, Simão Roberto, Martin Airton Abrahão, Moreira Leonardo Marmo. Creatine Supplementation in Wistar Rats Submitted to Physical Tests of Swimming: Evaluation of the Physiological Effects through Raman Spectroscopy. British Journal of Pharmaceutical Research. 2011 Apr-Jun; 1(2): 19-28.