Role of 5-hydroxytryptamine in Moringa oleifera induced potentiation of pentobarbitone hypnosis in albino rats.

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dc.contributor.authorRay, Kausiken_US
dc.contributor.authorHazra, Rimien_US
dc.contributor.authorDebnath, Pratip Kren_US
dc.contributor.authorGuha, Debjanien_US
dc.date.accessioned2009-05-28T13:00:10Z
dc.date.available2009-05-28T13:00:10Z
dc.date.issued2004-06-21en_US
dc.description.abstractThe role of 5-hydroxytryptamine (5-HT) in pentobarbitone (PB) sleeping time, gross behaviour, electrical activity of the brain and serum 5-HT level was studied in Holtzman strain adult albino rats following treatment with M. oleifera (MO). MO (350mg/kg) caused inhibition of awareness, touch response, motor activity, righting reflex, and grip strength. It significantly increased the PB sleeping time, serum 5-HT level (P<0.001) and alpha-wave activity. These observations indicate that the aqueous extract of MO potentiated PB induced sleeping time and increased the alpha-wave activity through 5-HT.en_US
dc.description.affiliationNeurophysiology Laboratory, Department of Physiology, University of Calcutta, 92, A.P.C. Road, Kolkata 700 009, India.en_US
dc.identifier.citationRay K, Hazra R, Debnath PK, Guha D. Role of 5-hydroxytryptamine in Moringa oleifera induced potentiation of pentobarbitone hypnosis in albino rats. Indian Journal of Experimental Biology. 2004 Jun; 42(6): 632-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/58833
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBehavior, Animal --drug effectsen_US
dc.subject.meshBrain --metabolismen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshElectroencephalographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFree Radical Scavengers --pharmacologyen_US
dc.subject.meshHypnosisen_US
dc.subject.meshMaleen_US
dc.subject.meshPentobarbital --pharmacologyen_US
dc.subject.meshRatsen_US
dc.subject.meshSerotonin --blooden_US
dc.subject.meshSleepen_US
dc.subject.meshTime Factorsen_US
dc.titleRole of 5-hydroxytryptamine in Moringa oleifera induced potentiation of pentobarbitone hypnosis in albino rats.en_US
dc.typeJournal Articleen_US
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