Impact of feeding ethanolic extract of root bark of Cananga odorata (Lam) on reproductive functions in male rats.

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dc.contributor.authorAnitha, Pen_US
dc.contributor.authorIndira, Men_US
dc.date.accessioned2009-05-28T11:23:09Z
dc.date.available2009-05-28T11:23:09Z
dc.date.issued2006-12-21en_US
dc.description.abstractThe 50% ethanolic extract of the root bark of C. odorata administered orally at the dose of 1g/kg body weight/day for 60 days resulted in decreased epididymal sperm motility and sperm count in male albino rats. Morphological abnormalities were also observed in the sperms. The testicular glycogen, the activities of 3beta hydroxy steroid dehydrogenase, glucose 6-phosphate dehydrogenase, malic enzyme, sorbitol dehydrogenase in seminal vesicle, fructose in seminal plasma and serum testosterone were significantly decreased in treated group. While testicular cholesterol level, the concentration of the fecal bile acids, urinary excretion of 17 ketosteroids, the activities of 17beta hydroxy steroid dehydrogenase, epididymal lactate dehydrogenase and that of testicular HMG CoA reductase were increased in treated group when compared to control. The results suggest that the ethanolic extract of C. odorata possesses the spermatotoxic effects in male albino rats.en_US
dc.description.affiliationDepartment of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram 695 581, India.en_US
dc.identifier.citationAnitha P, Indira M. Impact of feeding ethanolic extract of root bark of Cananga odorata (Lam) on reproductive functions in male rats. Indian Journal of Experimental Biology. 2006 Dec; 44(12): 976-80en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56642
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.source.urihttps://nopr.niscair.res.in/bitstream/123456789/6668/1/IJEB%2044%2812%29%20976-980.pdfen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnnonaceae --chemistryen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshEthanol --chemistryen_US
dc.subject.meshMaleen_US
dc.subject.meshPlant Extracts --administration & dosageen_US
dc.subject.meshRatsen_US
dc.subject.meshReproduction --drug effectsen_US
dc.titleImpact of feeding ethanolic extract of root bark of Cananga odorata (Lam) on reproductive functions in male rats.en_US
dc.typeJournal Articleen_US
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