Virus enhancement following infection with antibody-coated infectious bursal disease virus (IBDV) in chickens.

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dc.contributor.authorKumar, Ren_US
dc.date.accessioned2009-05-28T13:34:18Z
dc.date.available2009-05-28T13:34:18Z
dc.date.issued2001-12-23en_US
dc.description.abstractA novel concept of vaccination, employing virus-antibody complex has been reported for the control of infectious bursal disease in chickens. A comparison of virus replication, serum neutralizing antibody response and pathogenicity in chickens inoculated with the antibody coated virus, prepared by mixing virus and antibody in different ratios (1:1, 1:0.1, 1: 0.01) and virus alone without antibody, has been made. Antibody coated virus (when mixed in certain crucial ratios) replicated to a higher magnitude in the target organ, caused more severe pathogenesis but induced a primary serum neutralizing antibody response almost comparable. The results may have important implications in understanding of pathogenesis and development of control strategies against infectious bursal disease virus, specially employing immune complex vaccine.en_US
dc.description.affiliationDept. of Veterinary Microbiology, College of Veterinary Sciences, Chaudhary Charan Singh Haryana Agricultural University, Hisar, India.en_US
dc.identifier.citationKumar R. Virus enhancement following infection with antibody-coated infectious bursal disease virus (IBDV) in chickens. Indian Journal of Experimental Biology. 2001 Dec; 39(12): 1314-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/59584
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntibodies, Viral --immunologyen_US
dc.subject.meshBirnaviridae Infections --virologyen_US
dc.subject.meshChickensen_US
dc.subject.meshInfectious bursal disease virus --immunologyen_US
dc.titleVirus enhancement following infection with antibody-coated infectious bursal disease virus (IBDV) in chickens.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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