Effect of rhinax on bacterial lipopolysaccharide induced endotoxemia in rats.

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dc.contributor.authorDhuley, J Nen_US
dc.contributor.authorNaik, S Ren_US
dc.date.accessioned2009-05-28T15:49:26Z
dc.date.available2009-05-28T15:49:26Z
dc.date.issued1998-03-01en_US
dc.description.abstractAdministration of lipopolysaccharide (LPS) at 3 mg/kg, i.p. in rats resulted in reduced food intake, febrile hyperthermia, decreased body weight and reduced muscle performance in treadmill tests. It also induced some biochemical changes like increased serum levels of transaminases, acid phosphatase, pseudocholinesterase, free fatty acids and decreased blood glucose and liver glycogen levels. Rhinax (RHX), a herbal formulation, at 160 mg/kg, p.o. improved muscle performance but had no effect on the elevated temperature or the reduced body weight of rats weakened by LPS. It also normalised various biochemical alterations induced by LPS. The results of these studies indicate efficacy of RHX as an antifatigue agent to improve muscular performance.en_US
dc.description.affiliationDepartment of Pharmacology & Toxicology, Research Centre, Hindustan Antibiotics Ltd, Pune, India.en_US
dc.identifier.citationDhuley JN, Naik SR. Effect of rhinax on bacterial lipopolysaccharide induced endotoxemia in rats. Indian Journal of Experimental Biology. 1998 Mar; 36(3): 315-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/62459
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshEndotoxemia --chemically induceden_US
dc.subject.meshLipopolysaccharides --antagonists & inhibitorsen_US
dc.subject.meshPhytotherapyen_US
dc.subject.meshRatsen_US
dc.titleEffect of rhinax on bacterial lipopolysaccharide induced endotoxemia in rats.en_US
dc.typeJournal Articleen_US
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