In vitro anticancer activity of extracts of Mentha Spp. against human cancer cells.

Simple item page
dc.contributor.authorSharma, Vikas
dc.contributor.authorHussain, Shabir
dc.contributor.authorGupta, Moni
dc.contributor.authorSaxena, Ajit Kumar
dc.date.accessioned2014-12-29T09:39:36Z
dc.date.available2014-12-29T09:39:36Z
dc.date.issued2014-10
dc.description.abstractIn vitro anticancer potential of methanolic and aqueous extracts of whole plants of Mentha arvensis, M. longifolia, M. spicata and M. viridis at concentration of 100 µg/ml was evaluated against eight human cancer cell lines — A-549, COLO-205, HCT-116, MCF-7, NCI-H322, PC-3, THP-1 and U-87MG from six different origins (breast, colon, glioblastoma, lung, leukemia and prostate) using sulphorhodamine blue (SRB) assay. Methanolic extracts of above-mentioned Mentha Spp. displayed anti-proliferative effect in the range of 70-97% against four human cancer cell lines, namely COLO-205, MCF-7, NCI-H322 and THP-1; however, aqueous extracts were found to be active against HCT-116 and PC-3. The results indicate that Mentha Spp. contain certain constituents with cytotoxic properties which may find use in developing anticancer agents.en_US
dc.identifier.citationSharma Vikas, Hussain Shabir, Gupta Moni, Saxena Ajit Kumar. In vitro anticancer activity of extracts of Mentha Spp. against human cancer cells. Indian Journal of Biochemistry & Biophysics. 2014 Oct; 51(5): 416-419.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/154274
dc.language.isoenen_US
dc.publisherNISCAIR CSIR India.en_US
dc.source.urihttps://nopr.niscair.res.in/handle/123456789/29893en_US
dc.subjectMentha Spp.en_US
dc.subjectCancer cellsen_US
dc.subjectSRB assayen_US
dc.subject.meshAntineoplastic Agents --pharmacology
dc.subject.meshApoptosis --drug effects
dc.subject.meshCell Lint Tumor
dc.subject.meshCell Survival --drug effects
dc.subject.meshDose-Response Relationship, Drug
dc.subject.meshHumans
dc.subject.meshMentha --chemistry
dc.subject.meshMentha --classification
dc.subject.meshNeoplasms, Experimental --drug therapy
dc.subject.meshNeoplasms, Experimental --pathology
dc.subject.meshPlant Extracts --pharmacology
dc.subject.meshSpecies Specificity
dc.subject.otherPhytotherapy --methods
dc.titleIn vitro anticancer activity of extracts of Mentha Spp. against human cancer cells.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijbb2014v51n5p416.pdf
Size:
39.34 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Biochemistry & Biophysics