Leptin level in Thai children and adolescents: Relation to BMI and sexes.

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dc.contributor.authorChaichanwatanakul, Katharee
dc.contributor.authorWeerakulwattana, Praewvarin
dc.contributor.authorNunloi, Sunattra
dc.contributor.authorKomoltri, Chulaluk
dc.contributor.authorNakavachara, Pairunyar
dc.contributor.authorSantiprabhob, Jeerunda
dc.contributor.authorLikitmaskul, Supawadee
dc.date.accessioned2012-02-13T07:54:53Z
dc.date.available2012-02-13T07:54:53Z
dc.date.issued2006-09
dc.description.abstractObjective: The prevalence of obesity is rapidly increasing worldwide, including Thai children. Serum leptin is demonstrated largely that it increased in the dynamic phase in childhood –onset obesity. To our knowledge, there was no data of leptin measurement in this age group of our population. Methods: Therefore, we measured serum leptin by an immunoradiometric assay in sample from 208 obese and non-obese healthy children aged 2-18 years old. Its relationship to body mass index (BMI), ages and sexes were analyzed. Results: The mean serum leptin concentration in obese children was 35.06 + 17.31 ng/ml compared with 14.70 + 8.93 ng/ml in the non - obese children (p < 0.001). The obese female had significant higher level than in obese male group (43.26 + 16.82 vs. 30.34 + 15.85 ng/ml; p < 0.001), but they were not different in the non - obese group. The results showed that serum leptin correlated with BMI (r = 0.71; p < 0.001) and with % weight for height (%wt for ht) (r = 0.60, p < 0.001), respectively. Leptin levels in both sexes compared to age were also demonstrated. We did not find leptin deficiency or leptin resistance in all obese cases. Conclusion: In summary, leptin level in Thai children were increased according to BMI, % wt for ht and sexes as demonstrated in other ethnic groups. However, there is neither leptin deficiency nor leptin resistance demonstrated in this study.en_US
dc.identifier.citationChaichanwatanakul Katharee, Weerakulwattana Praewvarin, Nunloi Sunattra, Komoltri Chulaluk, Nakavachara Pairunyar, Santiprabhob Jeerunda, Likitmaskul Supawadee. Leptin level in Thai children and adolescents: Relation to BMI and sexes. Siriraj Medical Journal, 2006 Sept; 58(9): 1006-1009.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/136960
dc.language.isoenen_US
dc.source.urihttps://www.sirirajmedj.com/content_download.php?content_id=2054en_US
dc.subjectBMIen_US
dc.subjectLeptinen_US
dc.subjectNon-obeseen_US
dc.subjectObeseen_US
dc.titleLeptin level in Thai children and adolescents: Relation to BMI and sexes.en_US
dc.typeArticleen_US
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