Plantago major synthesized silver nanoparticles in an anti-acne facial sheet mask: physical stability, safety, and efficacy

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dc.contributor.authorAvanti, Cen_US
dc.contributor.authorMuftilana, Aen_US
dc.contributor.authorFiesta, Ben_US
dc.contributor.authorRani, KCen_US
dc.contributor.authorSukweenadhi, Jen_US
dc.contributor.authorKartini, Ken_US
dc.contributor.authorMago, RGen_US
dc.contributor.authorDevi, WVen_US
dc.contributor.authorWulansari, DDen_US
dc.contributor.authorKirtishanti, A.en_US
dc.date.accessioned2024-11-30T07:55:43Z
dc.date.available2024-11-30T07:55:43Z
dc.date.issued2024-09
dc.description.abstractThis study explores a novel approach to treat acne using silver nanoparticles (AgNPs) synthesized from Plantago major (Pm). We aimed to create a stable, safe, and effective anti-acne sheet mask. AgNPs were synthesized using water extracts of Pm leaves and formulated into an anti-acne sheet mask. The sheet mask was assessed for physical stability through freeze-thaw cycling tests and evaluated for safety through dermal irritation tests. The efficacy was assessed on the sheet mask’s impact on Propionibacterium acnes bacteria and inflammation. The anti-acne sheet mask containing AgNPs synthesized from Pm was found to be physically stable and safe for use, with no significant skin irritation observed. The formulation exhibited effective inhibition of P. acnes, particularly in the formula containing only AgNPs. In addition, the sheet mask preparations demonstrated substantial anti-inflammatory activity. The anti-acne sheet mask containing AgNPs synthesized from Pm exhibited favorable safety profile, inhibited P. acnes bacteria, and possessed anti-inflammatory properties.en_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Plant Biotechnology, Faculty of Biotechnology, University of Surabaya Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutical Biology, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Clinical Pharmacy, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Clinical Pharmacy, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Clinical Pharmacy, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesiaen_US
dc.identifier.affiliationsDepartment of Clinical Pharmacy, Faculty of Pharmacy, University of Surabaya, Surabaya, Indonesia.en_US
dc.identifier.citationAvanti C, Muftilana A, Fiesta B, Rani KC, Sukweenadhi J, Kartini K, Mago RG, Devi WV, Wulansari DD, Kirtishanti A.. Plantago major synthesized silver nanoparticles in an anti-acne facial sheet mask: physical stability, safety, and efficacy. Journal of Applied Biology & Biotechnology. 2024 Sep; 12(5): 161-169en_US
dc.identifier.issn2549-7005
dc.identifier.issn2347-212X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/236659
dc.languageenen_US
dc.publisherOpen Science Publishers LLPen_US
dc.relation.issuenumber5en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.7324/JABB.2024.169385en_US
dc.subjectAnti-acneen_US
dc.subjectSheet masken_US
dc.subjectSilver nanoparticlesen_US
dc.subjectPlantago majoren_US
dc.subjectSafetyen_US
dc.subjectEfficacy.en_US
dc.titlePlantago major synthesized silver nanoparticles in an anti-acne facial sheet mask: physical stability, safety, and efficacyen_US
dc.typeJournal Articleen_US
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