Seroprevalence of TORCH infection among pregnant women

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dc.contributor.authorSahu, Susanta Kumaren_US
dc.contributor.authorPradhan, Subrat Kumaren_US
dc.contributor.authorNayak, Lal Mohanen_US
dc.date.accessioned2020-05-06T08:41:19Z
dc.date.available2020-05-06T08:41:19Z
dc.date.issued2019-05
dc.description.abstractBackground: TORCH infection complex during pregnancy has bad obstetric outcomes starting from low birth weight to congenital anomalies, sensory neural deafness, mental retardation, cerebral palsy and sometimes to fatal outcomes like abortion and still birth. As these diseases remain mostly asymptomatic these are rarely tested during pregnancy. Serology is the mainstay of diagnosing these infections.. Methods: A cross sectional study was undertaken to estimate the burden of these infections in a rural belt of western Odisha where majority of the population depend upon agricultural work. A total number of 402 antenatal cases were screened by ELISA test for presence of IgG&IgM antibodies against toxoplasma, rubella virus, cytomegalovirus (CMV), herpes simplex virus (HSV) 1 & 2; RPR test was done to know seroprevalence of Syphilis. Results: It was found that Rubella is the most predominant infection being positive in 69.1% of the cases (IgG 68.4%, IgM 0.5%, and both IgG&IgM 0.25%), followed by CMV infection-66.7% (IgG 57.2%, IgM 1.7%, both 7.7%), Toxoplasma infection-39.8% (IgG 38.3%, IgM 0.7%, both 0.7%), HSV 1-23.6% (IgG 21.1%, IgM 2%, both 0.25%) and HSV 2 – 13.2% (IgG 11.7%, IgM 1.6%, both 0.25%). The seoprevalence of syphilis by RPR was least common with 0.5%. Conclusions: This study showed that most of the infections have occurred by 20 years of age and before or during the 1st pregnancy. It is less common among the antenatal cases who have better education and have spouses servicing in private or government sectors signifying the more health and sanitation awareness among this group.en_US
dc.identifier.affiliationsDepartment of Microbiology, SLN Medical College, Koraput, Odisha, Indiaen_US
dc.identifier.affiliationsDepartment of Community Medicine, VSS Institute of Medical Sciences and Research, Burla, Odisha, Indiaen_US
dc.identifier.affiliationsDepartment of Obstetrics & Gynaecology, VSS Institute of Medical Sciences and Research, Burla, Odisha, Indiaen_US
dc.identifier.citationSahu Susanta Kumar, Pradhan Subrat Kumar, Nayak Lal Mohan. Seroprevalence of TORCH infection among pregnant women. International Journal of Community Medicine and Public Health. 2019 May; 6(5): 2189-2194en_US
dc.identifier.issn2394-6032
dc.identifier.issn2394-6040
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/201411
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber5en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.18203/2394-6040.ijcmph20191842en_US
dc.subjectTORCHen_US
dc.subjectCogenital infectionen_US
dc.subjectToxoplasmaen_US
dc.subjectRubellaen_US
dc.subjectCytomegalovirus infectionen_US
dc.subjectHerpes simplexen_US
dc.titleSeroprevalence of TORCH infection among pregnant womenen_US
dc.typeJournal Articleen_US
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