The impact of therapy on the quality of life in asymptomatic patients with freshly detected hypertension

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dc.contributor.authorMishra, Satish Chandraen_US
dc.contributor.authorSingh, Vishalen_US
dc.contributor.authorPrakash, Sudeepen_US
dc.contributor.authorPandey, Pushkaren_US
dc.date.accessioned2020-04-23T07:58:06Z
dc.date.available2020-04-23T07:58:06Z
dc.date.issued2019-09
dc.description.abstractBackground: Hypertension is an commonly encountered disease which adversely affect all aspects of quality of life (QoL). The existing studies are confounded by the presence of multiple comorbidities and inclusion of elderly, which by themselves impairs the QoL. There is thus a need to study the impact of hypertension on QoL, in isolation.Method: This is a single center, prospective, intention to treat, observation study. The aim of the study is to evaluate the change in the QoL over six months, in newly diagnosed asymptomatic patients of hypertension. The tools used to assess the QoL included World Health Organisation’s Quality of Life Questionnaire (WHOQOL- BREF) and Short Form-36 (SF-36).Result: A total of 232 patients (172 males and 60 females) were enrolled in the study. The mean age was 44.66 years. A total of 102 patients (43.97%) had stage-1 and 130 patients (56.03%) had stage-2 hypertension. The female gender is associated with a higher likelihood of presentation with stage-2 hypertension. The male cohort had a better baseline QoL. The desired blood pressures was achieved in 40.52%. With therapy, the QoL improved significantly; sub-hoc analysis showed, the improvement was higher in males and those with stage-1 hypertension. There is an inverse relationship between the QoL and requirement for higher number of antihypertensive mediations.Conclusions: In patients with asymptomatic primary hypertension, treatment improves all aspects of QoL. The factors adversely affecting the QoL include female gender, higher stage of hypertension, poor blood pressure control and requirement of higher numbers of antihypertensive medicine.en_US
dc.identifier.affiliationsDepartment of Medicine, 7AF Hospital, Kanpur Cantt Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Nephrology, Army Hospital, New Delhi, Indiaen_US
dc.identifier.citationMishra Satish Chandra, Singh Vishal, Prakash Sudeep, Pandey Pushkar. The impact of therapy on the quality of life in asymptomatic patients with freshly detected hypertension. International Journal of Basic & Clinical Pharmacology. 2019 Sep; 8(9): 1983-1988en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200356
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber9en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2319-2003.ijbcp20193612en_US
dc.subjectHypertensionen_US
dc.subjectQuality of lifeen_US
dc.subjectShort form 36en_US
dc.subjectWHOQOLen_US
dc.titleThe impact of therapy on the quality of life in asymptomatic patients with freshly detected hypertensionen_US
dc.typeJournal Articleen_US
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