A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports.
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Date
2016-11
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Abstract
Osteopetrosis is a rare genetic bone disorder arising due to a defect in the differentiation or
function of osteoclast which results in a generalized increase in bone mass. Osteomyelitis
is one of the most common complications because of decreased bone marrow function and
compromised blood supply. Radiologist plays a vital role in diagnosing osteopetrosis. Here,
we present two cases of autosomal dominant osteopetrosis Type II (ADO II) with secondary
osteomyelitis changes which were reported to our department. One of these two cases presented
with secondary osteomyelitis in both maxilla and mandible and features of rickets, which is
very rarely seen in ADO II. To the best of our knowledge, the presentation of rickets with ADO
is the first of its kind to be reported. In this paper, we describe the clinical and radiological
features leading to the diagnosis of ADO in these two patients. Further, a review of the literature
regarding ADO is discussed.
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Keywords
Autosomal dominant osteopetrosis, bone within bone, osteomyelitis, rickets
Citation
Jayachandran S, Kumar M Suresh. A paradoxical presentation of rickets and secondary osteomyelitis of the jaw in Type II autosomal dominant osteopetrosis: Rare case reports. Indian Journal of Dental Research. 2016 Nov-Dec; 27(6): 667-671.