Oral exfoliative cytology of smokers at discrete clinical stages using AgNOR staining.

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dc.contributor.authorSethi, Pen_US
dc.contributor.authorShah, P Men_US
dc.date.accessioned2009-05-28T07:41:07Z
dc.date.available2009-05-28T07:41:07Z
dc.date.issued2003-07-29en_US
dc.description.abstractOBJECTIVE: This study was designed to evaluate oral exfoliative cytology of smokers without any clinically evident lesion and smokers with leukoplakia or oral cancer using AgNOR staining. STUDY DESIGN: Cytological smears of 30 smokers without lesion, 30 smokers with leukoplakia, 30 smokers with oral cancer and 30 non-smokers (control group) were studied using one step silver staining method. The AgNOR count was established on 100 cells. Mean AgNOR count and mean % of cells with 5 or more AgNORs was evaluated. The count values of groups were compared and analysed using Student's unpaired t-test. RESULTS: The mean AgNOR count for control group was 2.94 +/- 0.325, smokers without lesion 3.79 +/- 0.480 smokers with leukoplakia 3.89 +/- 0.433 and oral cancer 4.96 +/- 0.467. Mean % of cells with 5 or more AgNORs was 11.7, 26.5, 30.2 and 55.8 for control group, smokers without lesion, smokers with leukoplakia and oral cancer respectively. CONCLUSION: Analysis of AgNORs suggest that smoking influences proliferative activity in cells of smokers without any clinical lesion and that oral cancer shows highest proliferative activity.en_US
dc.description.affiliationDepartment of Oral Pathology, Govt. Dental College, Rohtak and Ahmedabad, India. drnaturebakshi@indiatimes.comen_US
dc.identifier.citationSethi P, Shah PM. Oral exfoliative cytology of smokers at discrete clinical stages using AgNOR staining. Indian Journal of Dental Research. 2003 Jul-Sep; 14(3): 142-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/51517
dc.language.isoengen_US
dc.source.urihttps://www.ijdr.inen_US
dc.subject.meshCytodiagnosis --methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLeukoplakia, Oral --pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMouth Mucosa --pathologyen_US
dc.subject.meshMouth Neoplasms --pathologyen_US
dc.subject.meshNucleolus Organizer Region --pathologyen_US
dc.subject.meshSilver Stainingen_US
dc.subject.meshSmoking --pathologyen_US
dc.titleOral exfoliative cytology of smokers at discrete clinical stages using AgNOR staining.en_US
dc.typeJournal Articleen_US
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