Lectin mediated binding of Streptococcus pyogenes to human oropharyngeal mucosal epithelial cells.

Simple item page
dc.contributor.authorKumar, K Sen_US
dc.contributor.authorGanguly, N Ken_US
dc.contributor.authorAnand, I Sen_US
dc.contributor.authorWahi, P Len_US
dc.date.accessioned2009-05-28T15:04:31Z
dc.date.available2009-05-28T15:04:31Z
dc.date.issued1996-03-01en_US
dc.description.abstractThe study was carried out to determine the role of lectins and sugars in the adhesion of S. pyogenes to human pharyngeal and buccal epithelial cells. In vitro adhesion assay has shown that Con A and Dolicos biflorus lectins inhibited the attachment of S. pyogenes to the oropharyngeal mucosal cells. Among different sugars used, N-acetyl-D-galactosamine and D-galactose have significantly blocked the binding of streptococci to PEC and BEC. These findings indicate that lectins and sugar molecules mediate the adhesion of S. pyogenes to the pharyngeal epithelial cells which may be important in the cellular pathogenesis of streptococcal infections which originate at the human oropharyngeal mucosa.en_US
dc.description.affiliationDepartment of Experimental Medicine and Biotechnology, and Cardiology, Postgraduate Institute of Medical Education-and Research, Chandigarh, India.en_US
dc.identifier.citationKumar KS, Ganguly NK, Anand IS, Wahi PL. Lectin mediated binding of Streptococcus pyogenes to human oropharyngeal mucosal epithelial cells. Indian Journal of Experimental Biology. 1996 Mar; 34(3): 270-1en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/61523
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshEpithelial Cellsen_US
dc.subject.meshHumansen_US
dc.subject.meshLectins --metabolismen_US
dc.subject.meshMouth Mucosa --cytologyen_US
dc.subject.meshPharynx --cytologyen_US
dc.subject.meshProtein Bindingen_US
dc.subject.meshStreptococcus pyogenes --metabolismen_US
dc.titleLectin mediated binding of Streptococcus pyogenes to human oropharyngeal mucosal epithelial cells.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Experimental Biology