Epstein-Barr virus (EBV) DNAemia in saliva of viral encephalitis and nasopharyngeal carcinoma patients

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dc.contributor.authorSrinivasan, Nen_US
dc.contributor.authorBarani, Ren_US
dc.contributor.authorManickavasagan, Men_US
dc.contributor.authorSrikanth, Pen_US
dc.date.accessioned2025-06-19T05:55:12Z
dc.date.available2025-06-19T05:55:12Z
dc.date.issued2025-03
dc.description.abstractEpstein?Barr virus (EBV) is a lymphotropic virus that causes diseases ranging from a flu?like illness called infectious mononucleosis to nasopharyngeal carcinoma, Burkitt’s lymphoma, and central nervous system (CNS) infection. Detection of EBV DNA is usually done using whole blood samples taken from the patients. We undertook the detection of EBV in blood, cerebrospinal fluid (CSF), and saliva by real?time quantitative PCR in two patients, one with a history of nasopharyngeal carcinoma, and the other having a case of viral encephalitis. EBV was detected only in saliva, whole blood in both patients, and CSF in the second case tested negative. This case series illustrates the importance of testing for EBV DNAemia in saliva by real?time polymerase chain reaction (PCR) to rule in a diagnosis of EBV.en_US
dc.identifier.affiliationsUndergraduate MBBS Student, Departments of Microbiologyen_US
dc.identifier.affiliationsMedical Oncology, Ramachandra Medical College and Research Institute, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsUndergraduate MBBS Student, Departments of Microbiologyen_US
dc.identifier.citationSrinivasan N, Barani R, Manickavasagan M, Srikanth P. Epstein-Barr virus (EBV) DNAemia in saliva of viral encephalitis and nasopharyngeal carcinoma patients. Indian Journal of Pathology & Microbiology. 2025 Mar; 68(1): 208-211en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/249955
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume68en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_356_23en_US
dc.subjectClinical awarenessen_US
dc.subjectEpstein?Barr virusen_US
dc.subjectreal?time quantitative PCRen_US
dc.subjectsalivaen_US
dc.titleEpstein-Barr virus (EBV) DNAemia in saliva of viral encephalitis and nasopharyngeal carcinoma patientsen_US
dc.typeJournal Articleen_US
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