First report on the detection of Japanese encephalitis virus in fruit bats from India

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dc.contributor.authorDhanze, Himanien_US
dc.contributor.authorMehta, Deepaen_US
dc.contributor.authorGupta, Meghaen_US
dc.contributor.authorMote, Akashen_US
dc.contributor.authorKumar, M Sumanen_US
dc.contributor.authorPawde, A Men_US
dc.contributor.authorKarikalan, Men_US
dc.date.accessioned2023-06-17T08:44:49Z
dc.date.available2023-06-17T08:44:49Z
dc.date.issued2022-04
dc.description.abstractJapanese encephalitis (JE) is a mosquito borne viral zoonotic disease and JE virus (JEV) is responsible for causing several children deaths every year in India. Since 1978, cases of JE have been reported from Gorakhpur district of Uttar Pradesh state annually. The knowledge on the role played by wildlife reservoirs in the sylvatic transmission and maintenance of JE virus remains limited. Bats are reservoir hosts for several emerging and re-emerging viral pathogens but their role in zoonotic cycle of JEV has not been elucidated yet. In Gorakhpur district of Uttar Pradesh, 52 fruit bats were found dead on 26 May 2020. The post-mortem report of the bat samples conducted at the Indian Veterinary Research Institute stated that the bats died due to brain hemorrhage, caused by excessive heat. The brain tissue samples of the bats were subjected to investigation using molecular techniques to determine the presence of JEV. The present work reports for the first time the detection of JEV in brain samples of bats from India. The viral load ranging from 8 to 18 copies/reaction was detected in brain samples by TaqMan real Time RT-PCR. The low viral load might be the reason for the absence of apparent clinical signs in bats and suggests the probable role of fruit bats in maintaining the JEV in nature.en_US
dc.identifier.affiliationsDivision of Veterinary Public Health, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Indiaen_US
dc.identifier.affiliationsCentre for Wildlife Conservation Management & Disease Surveillance, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Indiaen_US
dc.identifier.citationDhanze Himani, Mehta Deepa, Gupta Megha, Mote Akash, Kumar M Suman, Pawde A M, Karikalan M. First report on the detection of Japanese encephalitis virus in fruit bats from India. Journal of Vector Borne Diseases . 2022 Apr; 59(2): 190-192en_US
dc.identifier.issn0972-9062
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/216871
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber2en_US
dc.relation.volume59en_US
dc.source.urihttps://doi.org/10.4103/0972-9062.335769en_US
dc.subjectJapanese encephalitis virusen_US
dc.subjectTaqMan real-time RT-PCRen_US
dc.subjectFruit baten_US
dc.titleFirst report on the detection of Japanese encephalitis virus in fruit bats from Indiaen_US
dc.typeJournal Articleen_US
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