Biomass Fuel Use and Risk of Cataract: Systematic Review and Meta-Analysis.

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dc.contributor.authorKulkarni, Hemant
dc.contributor.authorNarlawar, Uday W
dc.contributor.authorSukhsohale, Neelam D
dc.contributor.authorThakre, Sushama
dc.contributor.authorUghade, Suresh N
dc.date.accessioned2016-03-01T11:37:08Z
dc.date.available2016-03-01T11:37:08Z
dc.date.issued2014-01-01
dc.description.abstractAims: There is an increasing recognition of the putative association between the use of biomass fuels and the risk of cataracts. However, the exact strength of this association is currently unknown. Our aim was to synthetically quantify the association between biomass fuel use and cataract. Study Design: Systematic review and meta-analysis. Methodology: Using results from the MEDLINE®, Scopus®, Web of Science® and Google® searches, we conducted a random-effects meta-analysis of the published studies. We also conducted subgroup meta-analyses, meta-regressions and sensitivity analyses to determine the contribution of potential confounders to between-study heterogeneity which was measured by the tau-squared and I2 statistics. Summary effect sizes (SES) were estimated using the DerSimonian and Laird method and the 95% confidence intervals (CI) and 95% prediction intervals (PI) were also estimated. Publication bias was examined using funnel plots and Egger’s test. Results: In spite of significant between-study heterogeneity (I2 70%, p=8.1x10-5), biomass fuel use was associated with a significantly increased risk of cataract (SES 2.12; 95% CI 1.61-2.80; 95% PI 0.88-5.09). Age-, gender- and other methodological differences did not significantly contribute to between-study heterogeneity but Indian studies showed a statistically significant association between biomass fuel use and cataract. Statistically homogeneous studies (n = 8) showed an SES of 2.01 (95% CI and PI 1.67-2.41). Conclusion: Synthetic evidence from observational studies indicates that biomass fuel use may increase the risk of cataract. Public health initiatives aimed at avoidance of biomass fuel use may reduce the burden of cataracts especially in settings where biomass fuels are commonly used.en_US
dc.identifier.citationKulkarni Hemant, Narlawar Uday W, Sukhsohale Neelam D, Thakre Sushama, Ughade Suresh N. Biomass Fuel Use and Risk of Cataract: Systematic Review and Meta-Analysis. British Journal of Medicine and Medical Research. 2014 Jan; 4(1): 382-394.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/174914
dc.language.isoenen_US
dc.source.urihttps://sciencedomain.org/abstract/2076en_US
dc.subjectBiomassen_US
dc.subjectcataracten_US
dc.subjectenergyen_US
dc.subjectindoor air pollutionen_US
dc.subjectmeta-analysisen_US
dc.titleBiomass Fuel Use and Risk of Cataract: Systematic Review and Meta-Analysis.en_US
dc.typeArticleen_US
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