Primary hyperparathyroidism due to parathyriod carcinoma: Report of a case and review of literature.
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Date
1997-05
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Abstract
A 21-year-old male with a history of bone pain for four months is described. He lost 2 cm of his height and also had polyuria and weight loss. Physical examination revealed a cachectic and mildly pale man with a firm mass of 0.8 cm in diameter on the fight side of his neck, generalized muscle wasting and proximal muscle weakness. kyphoscliosis and deformed thoracic cage. Skeletal X-ray showed finding compatible with the changes found in primary hyperparathyroidism. Biochemical parameters revealed a serum corrected total calcium of 15 mg/dl (8.5-10.5 mg/dl), inorganic phosphate of 3.7 mg/dl (305-5.0 mg/dl) and alkaline phosphatase of 1,008 U/l (39-117 U/l). Primary hyperparathyroidism was confirmed by a serum parathyroid hormone level of 1,733 pmol/l (0.100 pmol/l), Ultrasonography and computerized tomography of the neck showed a right neck mass with a diameter of 2 x 2.2 x 3 cm cm which was visualized by 99mTc-sestamibi scan. The patient underwent an uneventful surgical exploration of the neck. Histopathological study of the excised neck mass showed findings consistent with parathyroid carcinoma.
Description
Keywords
Primary hyperparathyroidism, Parathyriod carcinoma
Citation
Plengvidhya Nattachet, Sriussadaporn Sutin, Pusuwan Pawana, Wongbunnate Sommit, Bhothisuwan Kris, Vichayanrat Apichati, Vannasaeng Sathit, Nitiyanant Wannee, Peerapatdit Thavatchai. Primary hyperparathyroidism due to parathyriod carcinoma: Report of a case and review of literature. Siriraj Medical Journal, 1997 May; 49(5): 469-475.