Antihyperlipidemic activity of Chloroxylon swietenia in triton WR1339 induced hyperlipidemia

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dc.contributor.authorGuptha, B. H. M. R. K.en_US
dc.contributor.authorKadali, S. L. D. V. Ramana Murtyen_US
dc.contributor.authorM., Vijay Kumaren_US
dc.contributor.authorB. C., Revanasiddappaen_US
dc.date.accessioned2020-04-23T07:48:48Z
dc.date.available2020-04-23T07:48:48Z
dc.date.issued2018-03
dc.description.abstractBackground: Medicinal herbs are beneficial and effective either in the management and prevention of several metabolic disorders, associated with hyperlipidemia, hypertension and insulin resistance which increases the cardio-metabolic risk and demands for the life time therapy. Current allopathic medicines are expensive and reported with several adverse effects and hence, finding of a suitable herbal medicine for hyperlipidemic disorders is very important.Methods: Thirty albino rats weighing 200-230g were randomly divided into 5 groups were rendered hyperlipidemia with a single dose of triton WR 1339. Normal control, positive control, standard, aqueous and ethanolic extract groups were treated with tween-80, tween-80, atorvastatin, aqueous and ethanolic extracts of Chloroxylon swietenia respectively for seven days. At the end of the study, blood was collected for estimation of the lipid profile.Results: Both the aqueous and ethanolic extract groups significantly reduced the TG and VLDL levels.Conclusions: The extracts exhibited remarkable activity on one or either parameter of the lipid profile. It could be due to the presence of alkaloids, steroids, flavonoids, coumarins and phenols in the extracts.en_US
dc.identifier.affiliationsDepartment of Pharmacology, IQ City Medical College, Durgapur, West Bengal, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, Modern Institute of Medical Sciences, Indore, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences of Nitte University, Mangalore, Indiaen_US
dc.identifier.citationGuptha B. H. M. R. K., Kadali S. L. D. V. Ramana Murty, M. Vijay Kumar, B. C. Revanasiddappa. Antihyperlipidemic activity of Chloroxylon swietenia in triton WR1339 induced hyperlipidemia. International Journal of Basic & Clinical Pharmacology. 2018 Mar; 7(3): 518-523en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/199604
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2319-2003.ijbcp20180667en_US
dc.subjectChloroxylon swieteniaen_US
dc.subjectHyperlipidemiaen_US
dc.subjectTriton WR 1339en_US
dc.titleAntihyperlipidemic activity of Chloroxylon swietenia in triton WR1339 induced hyperlipidemiaen_US
dc.typeJournal Articleen_US
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