Review of the Literature on Oral Cancer: Epidemiology, Management and Evidence-based Traditional Medicine Treatment

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dc.contributor.authorCharly, M. M.en_US
dc.contributor.authorJean-PauI, S. I.en_US
dc.contributor.authorNgbolua, K.-T.-N.en_US
dc.contributor.authorHippolyte, S. N.-T.en_US
dc.contributor.authorErick, K. N.en_US
dc.contributor.authorAlifi, P. B.en_US
dc.contributor.authorAdelin, N. F.en_US
dc.contributor.authorMawunu, M.en_US
dc.contributor.authorMulongo, E. K.en_US
dc.contributor.authorAnne, T. M. N.en_US
dc.contributor.authorMpiana, P. T.en_US
dc.contributor.authorNestor, P. M.en_US
dc.date.accessioned2023-07-14T08:02:51Z
dc.date.available2023-07-14T08:02:51Z
dc.date.issued2022-06
dc.description.abstractOral cavity cancers are part of the upper aerodigestive tract cancers and represent a significant burden worldwide. Its epidemiology varies from country to country with high frequencies in South East Asian countries. Tobacco and alcohol are the main risk factors. Survival of oral cancer is low i.e., less than 40% in the advanced stage (stage III and IV), diagnosis of oral cavity cancer is based on a complete clinical examination of the oral cavity complete with biopsy, bio-markers are an adjunct to screening and diagnosis of oral cavity cancers, surgery, radiotherapy, chemotherapy and immunotherapy are part of the therapeutic armamentarium of oral cancer but also have limitations. Traditional medicine is an important and proven alternative in the treatment and support of patients with oral cavity cancer. Prevention of oral cavity cancers includes not only early detection of precancerous and cancerous lesions but also control of risk factors and education of the population. Surgery, radiotherapy, chemotherapy and immunotherapy are part of the therapeutic strategy of oral cancer treatment but also have limitations. Traditional Medicine is an important and proven alternative in the treatment and support of patients with oral cavity cancer. It is thus desirable to scientifically validate phytochemicals in order to integrate alternative medicine as part of national cancer management strategy. In silico advanced studies on secondary metabolites of medicinal plants traditionally used to treat oral cancer are in progress.en_US
dc.identifier.affiliationsFaculty of Dental Medicine, Service of Oral and Maxillofacial Surgery, University of Kinshasa, Kinshasa, Democratic Republic of the Congoen_US
dc.identifier.affiliationsFaculty of Dental Medicine, Service of Prosthodontics, University of Kinshasa, Kinshasa, Democratic Republic of the Congoen_US
dc.identifier.affiliationsFaculty of Science, Structural Biology and Chemo-informatics Unit, University of Kinshasa, Kinshasa, Democratic Republic of the Congoen_US
dc.identifier.affiliationsDepartment of Internal Medicine and Department of Tropical Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congoen_US
dc.identifier.affiliationsDepartment of Basic Sciences, Faculty of Medicine, University of Kinshasa, Democratic Republic of the Congoen_US
dc.identifier.affiliationsPolytechnic Institute of Kimpa Vita University, Uige, Republic of Angolaen_US
dc.identifier.affiliationsDepartment of Dentistry, Lingwala Referral Health Centre, Kinshasa, Democratic Republic of the Congoen_US
dc.identifier.affiliationsDepartment of Anatomo-Pathology, Faculty of Medicine, University of Kinshasa, Democratic Republic of the Congoen_US
dc.identifier.citationCharly M. M., Jean-PauI S. I., Ngbolua K.-T.-N., Hippolyte S. N.-T., Erick K. N., Alifi P. B., Adelin N. F., Mawunu M., Mulongo E. K., Anne T. M. N., Mpiana P. T., Nestor P. M. . Review of the Literature on Oral Cancer: Epidemiology, Management and Evidence-based Traditional Medicine Treatment. Annual Research & Review in Biology. 2022 Jun; 37(6): 15-27en_US
dc.identifier.issn2347-565X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/219344
dc.languageenen_US
dc.publisherSciencedomain Internationalen_US
dc.relation.issuenumber6en_US
dc.relation.volume37en_US
dc.source.urihttps://doi.org/10.9734/arrb/2022/v37i630512en_US
dc.subjectOral cavity canceren_US
dc.subjectupper aerodigestive tracten_US
dc.subjectEvidence-based medicineen_US
dc.subjectphytochemicalsen_US
dc.subjectmedicinal plantsen_US
dc.subjectalternative/ traditional medicineen_US
dc.titleReview of the Literature on Oral Cancer: Epidemiology, Management and Evidence-based Traditional Medicine Treatmenten_US
dc.typeJournal Articleen_US
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