Mentha piperita (Linn) leaf extract provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice.

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dc.contributor.authorSamarth, R Men_US
dc.contributor.authorSaini, M Ren_US
dc.contributor.authorMaharwal, Jen_US
dc.contributor.authorDhaka, Aen_US
dc.contributor.authorKumar, Ashoken_US
dc.date.accessioned2009-05-28T13:12:58Z
dc.date.available2009-05-28T13:12:58Z
dc.date.issued2002-11-19en_US
dc.description.abstractIntestinal protection in mice against radiation injury by M. piperita (1 g/kg body weight/day) was studied from day 1 to day 20 after whole body gamma irradiation (8 Gy). Villus height, goblet cells/villus section, total cells, mitotic cells and dead cells/crypt section in the jejunum are good parameters for the assessment of radiation damage. There was significant decrease in the villus height, number of total cells and mitotic cells/crypt section, whereas goblet cells and dead cells showed significant increase after irradiation. Mentha pretreatment resulted in a significant increase in villus height, total cells and mitotic cells, whereas goblet cells and dead cells showed a significant decrease from respective irradiated controls at each autopsy day. The results suggest that Mentha pretreatment provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice.en_US
dc.description.affiliationRadiation & Cancer Biology Laboratory, Department of Zoology, University of Rajasthan, Jaipur 302004, India.en_US
dc.identifier.citationSamarth RM, Saini MR, Maharwal J, Dhaka A, Kumar A. Mentha piperita (Linn) leaf extract provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice. Indian Journal of Experimental Biology. 2002 Nov; 40(11): 1245-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/59115
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCobalt Radioisotopesen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshDose-Response Relationship, Radiationen_US
dc.subject.meshGamma Raysen_US
dc.subject.meshIntestinal Mucosa --pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMentha piperitaen_US
dc.subject.meshMiceen_US
dc.subject.meshPhytotherapyen_US
dc.subject.meshPlant Extracts --therapeutic useen_US
dc.subject.meshPlant Leavesen_US
dc.subject.meshRadiation Injuries, Experimental --etiologyen_US
dc.subject.meshRadiation-Protective Agents --therapeutic useen_US
dc.subject.meshWhole-Body Irradiationen_US
dc.titleMentha piperita (Linn) leaf extract provides protection against radiation induced alterations in intestinal mucosa of Swiss albino mice.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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