Protective effect of Tribulus terrestris linn on liver and kidney in cadmium intoxicated rats.

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dc.contributor.authorLakshmi, G Dhana
dc.contributor.authorKumar, P Ravi
dc.contributor.authorBharavi, K
dc.contributor.authorAnnapurna, P
dc.contributor.authorRajendar, B
dc.contributor.authorPatel, Pankaj T
dc.contributor.authorKumar, C S V Satish
dc.contributor.authorRao, G S
dc.date.accessioned2013-02-25T07:50:29Z
dc.date.available2013-02-25T07:50:29Z
dc.date.issued2012-02
dc.description.abstractAdministration of cadmium (Cd) significantly increased the peroxidation markers such as malondialdehyde and protein carbonyls along with significant decrease in antioxidant markers such as super oxide dismutase and reduced glutathione in liver and kidney tissues. Cadmium also caused a significant alteration in hepatic and renal functional markers in serum viz. total protein, albumin, alanine transaminase, blood urea nitrogen and creatinine. Prominent pathological changes observed in liver were severe vascular and sinusoidal congestion with diffuse degenerative changes and mononuclear infiltration into peripheral areas, while the kidney showed vascular and glomerular congestion, cloudy swelling of tubular epithelium. Co-administration of ethonolic extract of T. terrestris or vitamin E along with Cd significantly reversed the Cd induced changes along with significant reduction in Cd load.en_US
dc.identifier.citationLakshmi G Dhana, Kumar P Ravi, Bharavi K, Annapurna P, Rajendar B, Patel Pankaj T, Kumar C S V Satish, Rao G S. Protective effect of Tribulus terrestris linn on liver and kidney in cadmium intoxicated rats. Indian Journal of Experimental Biology. 2012 Feb; 50(2): 141-146.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/145234
dc.language.isoenen_US
dc.source.urihttps://nopr.niscair.res.in/handle/123456789/13570en_US
dc.subjectCadmiumen_US
dc.subjectKidneyen_US
dc.subjectLiveren_US
dc.subjectRatsen_US
dc.subjectTribulus Terrestrisen_US
dc.titleProtective effect of Tribulus terrestris linn on liver and kidney in cadmium intoxicated rats.en_US
dc.typeArticleen_US
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