Drug Delivery Through Blood Brain Barrier: Taming the Bottleneck in CNS Therapeutics

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dc.contributor.authorSehgal, VKen_US
dc.contributor.authorSingla, Ren_US
dc.date.accessioned2019-11-04T04:58:07Z
dc.date.available2019-11-04T04:58:07Z
dc.date.issued2018-07
dc.description.abstractAlthough many agents have therapeutic potentials for Central Nervous System (CNS) diseases, few of these agents have been clinically used because of the brain barriers. Physiological barriers like the blood-brain barrier and blood-cerebrospinal fluid barrier as well as various efflux transporter proteins make the entry of drugs into the central nervous system very difficult. Different strategies for efficient CNS delivery have been studied. This review presents the current approaches to facilitate penetration across these barriers for enhanced drug delivery to the CNS.en_US
dc.identifier.affiliationsProfessoren_US
dc.identifier.affiliationsPost Graduate Student, Department of Pharmacology, Government Medical College, Patiala, Punjab - 147001, India; singla.ritika1308@gmail.comen_US
dc.identifier.citationSehgal VK, Singla R. Drug Delivery Through Blood Brain Barrier: Taming the Bottleneck in CNS Therapeutics. International Journal of Medical and Dental Sciences. 2018 Jul; 7(2): 1653-1656en_US
dc.identifier.issn2454-8952
dc.identifier.issn2320-1118
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/183619
dc.languageenen_US
dc.publisherDr. J.S. Sodhi Memorial Educational Societyen_US
dc.relation.issuenumber2en_US
dc.relation.volume7en_US
dc.source.urihttps://doi.org/10.18311/ijmds/2018/20037en_US
dc.subjectBlood Brain Barrieren_US
dc.subjectCNS Drug Deliveryen_US
dc.subjectPharmacy and Pharmacologyen_US
dc.titleDrug Delivery Through Blood Brain Barrier: Taming the Bottleneck in CNS Therapeuticsen_US
dc.typeJournal Articleen_US
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