Dieldrin initiates apoptosis in rat thymocytes.

Simple item page
dc.contributor.authorHallegue, Dorsafen_US
dc.contributor.authorBen Rhouma, Khemaisen_US
dc.contributor.authorKrichah, Rajaen_US
dc.contributor.authorSakly, Mohsenen_US
dc.date.accessioned2009-05-28T15:35:16Z
dc.date.available2009-05-28T15:35:16Z
dc.date.issued2002-10-16en_US
dc.description.abstractIn vitro incubation for 6 hr to pesticide dieldrin resulted in a dose-dependent decrease of cell viability comparable to that of dexamethasone. In vivo experiments also demonstrated that dieldrin administration induced a dose-dependent thymic atrophy which appeared to be mediated by endogenous corticosteroids. Agarose gel electrophorosis analysis, revealed the generation of typical apoptotic oligosomal DNA fragmentation in presence of dieldrin. However, in response to high concentrations of pesticide, cells seemed to undergo necrosis pathway. Thus, it may be concluded that dieldrin induced apoptosis in rat thymocytes.en_US
dc.description.affiliationLaboratory of Animal Physiology, Sciences Faculty, 7021 Bizerta Tunisia.en_US
dc.identifier.citationHallegue D, Ben Rhouma K, Krichah R, Sakly M. Dieldrin initiates apoptosis in rat thymocytes. Indian Journal of Experimental Biology. 2002 Oct; 40(10): 1147-50en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/62164
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshApoptosis --drug effectsen_US
dc.subject.meshDieldrin --toxicityen_US
dc.subject.meshElectrophoresis, Agar Gelen_US
dc.subject.meshFemaleen_US
dc.subject.meshInsecticides --toxicityen_US
dc.subject.meshMaleen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshThymus Gland --cytologyen_US
dc.titleDieldrin initiates apoptosis in rat thymocytes.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Experimental Biology